Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50000299
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245656(CHEMBL4059780)
Affinity DataIC50: 16nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245656(CHEMBL4059780)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human CYP17 expressed in human A549 cell membranes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245683(CHEMBL4064141)
Affinity DataIC50: 21nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245683(CHEMBL4064141)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human CYP17 expressed in human A549 cell membranes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245664(CHEMBL4068802)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human CYP17 expressed in human A549 cell membranes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM25458(ABT | CHEMBL254328 | CB 7598 | (1S,2R,5S,10R,11S,1...)
Affinity DataIC50: 25nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245657(CHEMBL4101612)
Affinity DataIC50: 28nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245688(CHEMBL4083609)
Affinity DataIC50: 28nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245657(CHEMBL4101612)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human CYP17 expressed in human A549 cell membranes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245664(CHEMBL4068802)
Affinity DataIC50: 30nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245654(CHEMBL4063960)
Affinity DataIC50: 34nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM25458(ABT | CHEMBL254328 | CB 7598 | (1S,2R,5S,10R,11S,1...)
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human CYP17 expressed in human A549 cell membranes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245654(CHEMBL4063960)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant human CYP17 expressed in human A549 cell membranes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245655(CHEMBL4091726)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant human CYP17 expressed in human A549 cell membranes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245655(CHEMBL4091726)
Affinity DataIC50: 57nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245668(CHEMBL4083029)
Affinity DataIC50: 61nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245669(CHEMBL4077026)
Affinity DataIC50: 76nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245694(CHEMBL4101951)
Affinity DataIC50: 81nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245684(CHEMBL4085705)
Affinity DataIC50: 115nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245666(CHEMBL4083961)
Affinity DataIC50: 121nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245689(CHEMBL4093882)
Affinity DataIC50: 229nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245697(CHEMBL4077854)
Affinity DataIC50: 257nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245698(CHEMBL4072156)
Affinity DataIC50: 257nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245658(CHEMBL4090236)
Affinity DataIC50: 390nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245687(CHEMBL4091391)
Affinity DataIC50: 449nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245686(CHEMBL4063548)
Affinity DataIC50: 517nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245695(CHEMBL4072550)
Affinity DataIC50: 535nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245664(CHEMBL4068802)
Affinity DataIC50: 685nMAssay Description:Inhibition of human hepatic CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245667(CHEMBL4099464)
Affinity DataIC50: 980nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245696(CHEMBL4061151)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245672(CHEMBL4078455)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245685(CHEMBL4099128)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245673(CHEMBL4102114)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245671(CHEMBL4074529)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245670(CHEMBL4072728)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245665(CHEMBL4096103)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM25458(ABT | CHEMBL254328 | CB 7598 | (1S,2R,5S,10R,11S,1...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human hepatic CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245683(CHEMBL4064141)
Affinity DataIC50: 5.28E+3nMAssay Description:Inhibition of human hepatic CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245654(CHEMBL4063960)
Affinity DataIC50: 6.53E+3nMAssay Description:Inhibition of human hepatic CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245657(CHEMBL4101612)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of human hepatic CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245656(CHEMBL4059780)
Affinity DataIC50: 8.56E+3nMAssay Description:Inhibition of human hepatic CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245655(CHEMBL4091726)
Affinity DataIC50: 9.03E+3nMAssay Description:Inhibition of human hepatic CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed