Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50000639
TargetDelta-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256671(CHEMBL4085431)
Affinity DataEC50:  630nMAssay Description:Agonist activity at rat delta opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256672(CHEMBL4078283)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at rat mu opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataEC50:  146nMAssay Description:Agonist activity at rat mu opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256673(CHEMBL4102551)
Affinity DataEC50:  19nMAssay Description:Agonist activity at rat mu opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256687(CHEMBL4065923)
Affinity DataEC50:  2.20nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256674(CHEMBL4086171)
Affinity DataEC50:  797nMAssay Description:Agonist activity at rat mu opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256673(CHEMBL4102551)
Affinity DataEC50:  901nMAssay Description:Agonist activity at rat delta opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256675(CHEMBL4073254)
Affinity DataEC50:  2.06E+3nMAssay Description:Agonist activity at rat mu opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50217952((1R,5R,9S)-(-)-9-hydroxy-5-(3-hydroxyphenyl-2-phen...)
Affinity DataEC50:  22nMAssay Description:Agonist activity at rat mu opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256671(CHEMBL4085431)
Affinity DataEC50:  0.740nMAssay Description:Agonist activity at rat mu opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256672(CHEMBL4078283)
Affinity DataEC50:  253nMAssay Description:Agonist activity at rat delta opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50217952((1R,5R,9S)-(-)-9-hydroxy-5-(3-hydroxyphenyl-2-phen...)
Affinity DataEC50:  1.08E+3nMAssay Description:Agonist activity at rat delta opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM21008((4S,7S,13S)-13-[(2S)-2-amino-3-(4-hydroxyphenyl)pr...)
Affinity DataEC50:  368nMAssay Description:Agonist activity at rat delta opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256673(CHEMBL4102551)
Affinity DataEC50:  761nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256671(CHEMBL4085431)
Affinity DataKi:  0.0730nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50217952((1R,5R,9S)-(-)-9-hydroxy-5-(3-hydroxyphenyl-2-phen...)
Affinity DataKi:  0.265nMAssay Description:Agonist activity at rat mu opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256672(CHEMBL4078283)
Affinity DataKi:  0.741nMAssay Description:Agonist activity at rat mu opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256673(CHEMBL4102551)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataKi:  2.30nMAssay Description:Agonist activity at rat mu opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50039029(CHEMBL13470 | 3-[(4-Allyl-2,5-dimethyl-piperazin-1...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]DADLE from delta opioid receptor in rat brain after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM21130(U69,593 | N-methyl-N-(7-(1-pyrrolidinyl)-1-oxaspir...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in rat brain after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256671(CHEMBL4085431)
Affinity DataKi:  9.80nMAssay Description:Displacement of [3H]DADLE from delta opioid receptor in rat brain after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256674(CHEMBL4086171)
Affinity DataKi:  12nMAssay Description:Agonist activity at rat mu opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256672(CHEMBL4078283)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]DADLE from delta opioid receptor in rat brain after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50217952((1R,5R,9S)-(-)-9-hydroxy-5-(3-hydroxyphenyl-2-phen...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]DADLE from delta opioid receptor in rat brain after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256686(CHEMBL4064665)
Affinity DataKi:  25nMAssay Description:Agonist activity at rat mu opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256678(CHEMBL4093929)
Affinity DataKi:  27nMAssay Description:Agonist activity at rat mu opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256675(CHEMBL4073254)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256673(CHEMBL4102551)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in rat brain after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256677(CHEMBL4101657)
Affinity DataKi:  45nMAssay Description:Agonist activity at rat mu opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256676(CHEMBL4083659)
Affinity DataKi:  52nMAssay Description:Agonist activity at rat mu opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256671(CHEMBL4085431)
Affinity DataKi:  55nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in rat brain after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute On Drug Abuse and The National Institute On Alcohol Abuse

Curated by ChEMBL
LigandPNGBDBM50256673(CHEMBL4102551)
Affinity DataKi:  161nMAssay Description:Displacement of [3H]DADLE from delta opioid receptor in rat brain after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed