Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 8024
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Cambridge

LigandPNGBDBM228827(3-Cyclopentyl-1-(pyrrolidin-1-yl)propan-1-one (1))
Affinity DataKd:  1.20E+4nMAssay Description:An aqueous solution of the fragment to be tested (1 mM) was prepared containing NaCl (300 mM), Tris.HCl (20 mM, pH = 8.0), d6-DMSO (10% v/v) and glyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Cambridge

LigandPNGBDBM228828(Cyclopentylmethyl pyrrolidine-1-carboxylate (2))
Affinity DataKd:  1.50E+4nMAssay Description:An aqueous solution of the fragment to be tested (1 mM) was prepared containing NaCl (300 mM), Tris.HCl (20 mM, pH = 8.0), d6-DMSO (10% v/v) and glyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMed
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Cambridge

LigandPNGBDBM228829(N-(Cyclopentylmethyl)pyrrolidine-1-carboxamide (3))
Affinity DataKd:  6.00E+3nMAssay Description:An aqueous solution of the fragment to be tested (1 mM) was prepared containing NaCl (300 mM), Tris.HCl (20 mM, pH = 8.0), d6-DMSO (10% v/v) and glyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Cambridge

LigandPNGBDBM228830(N-(Cyclopentylmethyl)cyclopentanecarboxamide (4))
Affinity DataKd:  1.10E+4nMAssay Description:An aqueous solution of the fragment to be tested (1 mM) was prepared containing NaCl (300 mM), Tris.HCl (20 mM, pH = 8.0), d6-DMSO (10% v/v) and glyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Cambridge

LigandPNGBDBM228831(1-((2-Cyclopentylethyl)sulfonyl)pyrrolidine (5))
Affinity DataKd:  1.60E+4nMAssay Description:An aqueous solution of the fragment to be tested (1 mM) was prepared containing NaCl (300 mM), Tris.HCl (20 mM, pH = 8.0), d6-DMSO (10% v/v) and glyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Cambridge

LigandPNGBDBM228832(N-(Cyclopentylmethyl)pyrrolidine-1-sulfonamide (6))
Affinity DataKd:  2.00E+4nMAssay Description:An aqueous solution of the fragment to be tested (1 mM) was prepared containing NaCl (300 mM), Tris.HCl (20 mM, pH = 8.0), d6-DMSO (10% v/v) and glyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMed
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Cambridge

LigandPNGBDBM228833((E)-3-(Furan-3-yl)-1-(pyrrolidin-1-yl)prop-2-en-1-...)
Affinity DataKd:  2.00E+4nMAssay Description:An aqueous solution of the fragment to be tested (1 mM) was prepared containing NaCl (300 mM), Tris.HCl (20 mM, pH = 8.0), d6-DMSO (10% v/v) and glyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Cambridge

LigandPNGBDBM228834(3-(Furan-3-yl)-1-(pyrrolidin-1-yl)propan-1-one (8))
Affinity DataKd:  2.20E+4nMAssay Description:An aqueous solution of the fragment to be tested (1 mM) was prepared containing NaCl (300 mM), Tris.HCl (20 mM, pH = 8.0), d6-DMSO (10% v/v) and glyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)