Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50000749
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataKd:  0.590nMAssay Description:Binding affinity to human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataKd:  0.5nMAssay Description:Binding affinity to human CB1 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFatty-acid amide hydrolase 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260116(CHEMBL4072432)
Affinity DataIC50: 600nMAssay Description:Inhibition of FAAH in human U937 cells assessed as decrease in [ethanolamine-1-3H]AEA uptake preincubated for 2 mins followed by AEA addition after 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260117(CHEMBL4072884)
Affinity DataIC50: 700nMAssay Description:Inhibition of FAAH in human U937 cells assessed as decrease in [ethanolamine-1-3H]AEA uptake preincubated for 2 mins followed by AEA addition after 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260120(CHEMBL4071145)
Affinity DataIC50: 800nMAssay Description:Inhibition of FAAH in human U937 cells assessed as decrease in [ethanolamine-1-3H]AEA uptake preincubated for 2 mins followed by AEA addition after 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260119(FARINOSONE A)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of FAAH in human U937 cells assessed as decrease in [ethanolamine-1-3H]AEA uptake preincubated for 2 mins followed by AEA addition after 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260120(CHEMBL4071145)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of FAAH in human U937 cells assessed as decrease in [ethanolamine-1-3H]AEA uptake preincubated for 2 mins followed by AEA addition after 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260117(CHEMBL4072884)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human COX2 preincubated for 15 mins followed by arachidonic acid/2-OG substrate addition after 5 mins by ADHP probe-based f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260120(CHEMBL4071145)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human COX2 preincubated for 15 mins followed by arachidonic acid/2-OG substrate addition after 5 mins by ADHP probe-based f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260119(FARINOSONE A)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human COX2 preincubated for 15 mins followed by arachidonic acid/2-OG substrate addition after 5 mins by ADHP probe-based f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260118(CHEMBL4086242)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells assessed as decrease in [ethanolamine-1-3H]AEA uptake preincubated for 2 mins followed by AEA addition after 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260117(CHEMBL4072884)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells using [ethanolamine-1-3H]AEA as substrate after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260118(CHEMBL4086242)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human COX2 preincubated for 15 mins followed by arachidonic acid/2-OG substrate addition after 5 mins by ADHP probe-based f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260116(CHEMBL4072432)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human COX2 preincubated for 15 mins followed by arachidonic acid/2-OG substrate addition after 5 mins by ADHP probe-based f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260116(CHEMBL4072432)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells assessed as decrease in [ethanolamine-1-3H]AEA uptake preincubated for 2 mins followed by AEA addition after 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260119(FARINOSONE A)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells assessed as decrease in [ethanolamine-1-3H]AEA uptake preincubated for 2 mins followed by AEA addition after 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260118(CHEMBL4086242)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells using [ethanolamine-1-3H]AEA as substrate after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260118(CHEMBL4086242)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human CB1 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260116(CHEMBL4072432)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human CB1 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260120(CHEMBL4071145)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP55,940 from human CB2 receptor expressed in CHOK1 cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260118(CHEMBL4086242)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP55,940 from human CB2 receptor expressed in CHOK1 cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260117(CHEMBL4072884)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP55,940 from human CB2 receptor expressed in CHOK1 cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260116(CHEMBL4072432)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP55,940 from human CB2 receptor expressed in CHOK1 cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260119(FARINOSONE A)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CP55,940 from human CB2 receptor expressed in CHOK1 cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260120(CHEMBL4071145)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity to human CB1 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260117(CHEMBL4072884)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human CB1 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bern

Curated by ChEMBL
LigandPNGBDBM50260119(FARINOSONE A)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human CB1 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed