Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50049211
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236690(CHEMBL4063956)
Affinity DataEC50:  4.01E+4nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236699(CHEMBL4091211)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236698(CHEMBL4101950)
Affinity DataEC50:  57nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236696(CHEMBL4064922)
Affinity DataEC50:  2.71E+3nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236695(CHEMBL4063167)
Affinity DataEC50:  2.32E+3nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236694(CHEMBL4065921)
Affinity DataEC50:  1.48E+4nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236689(CHEMBL4091723)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GPR120 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236689(CHEMBL4091723)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PPARgamma (unknown origin) expressed in HEK293T cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50019085(CHEMBL3288346)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GPR120 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236692(CHEMBL4066238)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GPR120 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50019085(CHEMBL3288346)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PPARgamma (unknown origin) expressed in HEK293T cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236692(CHEMBL4066238)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PPARgamma (unknown origin) expressed in HEK293T cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236693(CHEMBL4088797)
Affinity DataEC50:  410nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236692(CHEMBL4066238)
Affinity DataEC50:  81nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236691(CHEMBL4080911)
Affinity DataEC50:  240nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236678(CHEMBL4071066)
Affinity DataEC50:  450nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236689(CHEMBL4091723)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236688(CHEMBL4083960)
Affinity DataEC50:  210nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236687(CHEMBL4094216)
Affinity DataEC50:  210nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236686(CHEMBL4102878)
Affinity DataEC50:  2.01E+3nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236685(CHEMBL4065959)
Affinity DataEC50:  580nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236684(CHEMBL4087365)
Affinity DataEC50:  82nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236683(CHEMBL4083913)
Affinity DataEC50:  640nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236682(CHEMBL4092577)
Affinity DataEC50:  2.42E+3nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50019085(CHEMBL3288346)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236681(CHEMBL4093521)
Affinity DataEC50:  1.47E+4nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236680(CHEMBL4074547)
Affinity DataEC50:  3.22E+4nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50339489(3-{4-[(2',6'-Dimethylbiphenyl-3-yl)methoxy]phenyl}...)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50386790(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
Affinity DataEC50:  27nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50236679(CHEMBL4073587)
Affinity DataEC50:  3.92E+3nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed