Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50049169
TargetDihydrofolate reductase(Human)
University of Torino

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquin...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Torino

Curated by ChEMBL
LigandPNGBDBM50235594(CHEMBL4105330)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Torino

Curated by ChEMBL
LigandPNGBDBM50235596(CHEMBL4098306)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Torino

Curated by ChEMBL
LigandPNGBDBM50235589(CHEMBL4090575)
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Torino

Curated by ChEMBL
LigandPNGBDBM50235597(CHEMBL4088968)
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Torino

Curated by ChEMBL
LigandPNGBDBM50235595(CHEMBL4081077)
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Torino

Curated by ChEMBL
LigandPNGBDBM50235593(CHEMBL4062046 | US12162877, Compound 2)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Torino

Curated by ChEMBL
LigandPNGBDBM50235590(CHEMBL4071260)
Affinity DataIC50: 108nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Torino

Curated by ChEMBL
LigandPNGBDBM50363559(CHEMBL1946659)
Affinity DataIC50: 289nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Torino

Curated by ChEMBL
LigandPNGBDBM50018011(CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE)
Affinity DataIC50: 388nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Torino

Curated by ChEMBL
LigandPNGBDBM50363564(CHEMBL1946851)
Affinity DataIC50: 599nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Torino

Curated by ChEMBL
LigandPNGBDBM50235592(CHEMBL4061824)
Affinity DataIC50: 853nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Torino

Curated by ChEMBL
LigandPNGBDBM50235591(CHEMBL4089886)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed