Compile Data Set for Download or QSAR
Report error Found 86 Enz. Inhib. hit(s) with all data for entry = 50048990
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232544(CHEMBL4099851)
Affinity DataIC50: 2.40nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232550(CHEMBL4062620)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50355882(CHEMBL591666)
Affinity DataIC50: 6.60nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232545(CHEMBL4078648)
Affinity DataIC50: 8.80nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232543(CHEMBL4096216)
Affinity DataIC50: 9.70nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232548(CHEMBL4094572)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232544(CHEMBL4099851)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232550(CHEMBL4062620)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232562(CHEMBL4066230)
Affinity DataIC50: 22nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232543(CHEMBL4096216)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232563(CHEMBL4095293)
Affinity DataIC50: 29nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232545(CHEMBL4078648)
Affinity DataIC50: 31nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232548(CHEMBL4094572)
Affinity DataIC50: 36nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232547(CHEMBL4065183)
Affinity DataIC50: 38nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50355882(CHEMBL591666)
Affinity DataIC50: 38nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232556(CHEMBL4095176)
Affinity DataIC50: 41nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232559(CHEMBL4089315)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232560(CHEMBL4061149)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232557(CHEMBL4074660)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232558(CHEMBL4095118)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232552(CHEMBL4074035)
Affinity DataIC50: 60nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232572(CHEMBL4064393)
Affinity DataIC50: 61nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232573(CHEMBL4102314)
Affinity DataIC50: 94nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232551(CHEMBL4084355)
Affinity DataIC50: 94nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232562(CHEMBL4066230)
Affinity DataIC50: 101nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232546(CHEMBL4103046)
Affinity DataIC50: 104nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232549(CHEMBL4092846)
Affinity DataIC50: 124nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232575(CHEMBL4102924)
Affinity DataIC50: 137nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232563(CHEMBL4095293)
Affinity DataIC50: 143nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232555(CHEMBL4086496)
Affinity DataIC50: 175nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232576(CHEMBL4072974)
Affinity DataIC50: 181nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232549(CHEMBL4092846)
Affinity DataIC50: 236nMAssay Description:Antagonist activity at human EP2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232547(CHEMBL4065183)
Affinity DataIC50: 254nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232567(CHEMBL4067234)
Affinity DataIC50: 302nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232549(CHEMBL4092846)
Affinity DataIC50: 317nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232574(CHEMBL4073631)
Affinity DataIC50: 340nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232568(CHEMBL4085097)
Affinity DataIC50: 370nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232553(CHEMBL4094257)
Affinity DataIC50: 400nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232564(CHEMBL4061595)
Affinity DataIC50: 545nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232546(CHEMBL4103046)
Affinity DataIC50: 575nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50355882(CHEMBL591666)
Affinity DataIC50: 709nMAssay Description:Antagonist activity at human EP2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232570(CHEMBL4083413)
Affinity DataIC50: 1.21E+3nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232547(CHEMBL4065183)
Affinity DataIC50: 1.29E+3nMAssay Description:Antagonist activity at human EP2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232545(CHEMBL4078648)
Affinity DataIC50: 1.62E+3nMAssay Description:Antagonist activity at human EP2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232554(CHEMBL4065050)
Affinity DataIC50: 1.79E+3nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232544(CHEMBL4099851)
Affinity DataIC50: 1.89E+3nMAssay Description:Antagonist activity at human EP2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232569(CHEMBL4087592)
Affinity DataIC50: 2.94E+3nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232548(CHEMBL4094572)
Affinity DataIC50: 3.32E+3nMAssay Description:Antagonist activity at human EP2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232543(CHEMBL4096216)
Affinity DataIC50: 4.36E+3nMAssay Description:Antagonist activity at human EP2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Askat

Curated by ChEMBL
LigandPNGBDBM50232577(CHEMBL4074849)
Affinity DataIC50: 5.00E+3nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
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