Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50049198
TargetNicotinamide phosphoribosyltransferase(Mouse)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50236217(CHEMBL4061448)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50236220(CHEMBL4074848)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM81395(APO-866 | US20240327418, Example FK866 | US2024030...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50236217(CHEMBL4061448)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of NAMPT in human Jurkat T cells assessed as reduction in NAD levelsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50236220(CHEMBL4074848)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of NAMPT in human Jurkat T cells assessed as reduction in NAD levelsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50236219(CHEMBL4066091)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of NAMPT in human Jurkat T cells assessed as reduction in NAD levelsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50236219(CHEMBL4066091)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50236221(CHEMBL4078882)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50236223(CHEMBL4083606)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50236222(CHEMBL4101611)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50236224(CHEMBL4088492)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50236216(CHEMBL4064240)
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50236218(CHEMBL4094769)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50236215(CHEMBL4087071)
Affinity DataIC50: 269nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed