Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50000919
Target4-hydroxyphenylpyruvate dioxygenase(Wild carrot)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50264378(CHEMBL4098026)
Affinity DataKd:  6nMAssay Description:Inhibition of carrot HPPD expressed in Escherichia coli JM105 using HPPA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50403921(CHEMBL309664)
Affinity DataIC50: 15nMAssay Description:Inhibition of pig liver HPPD using 4-hydroxyphenylpyruvic acid as substrate after 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Mouse-ear cress)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50264344(CHEMBL4082652)
Affinity DataIC50: 19nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli JM105 using 4-HPP as substrate preincubated for 15 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50403929(CHEMBL76394)
Affinity DataIC50: 28nMAssay Description:Inhibition of pig liver HPPD using 4-hydroxyphenylpyruvic acid as substrate after 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50089165(Cyclopropanecarboxylic acid 3-oxo-cyclohex-1-enyl ...)
Affinity DataIC50: 30nMAssay Description:Inhibition of pig liver HPPD using 4-hydroxyphenylpyruvic acid as substrate after 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50264347(CHEMBL4092919)
Affinity DataIC50: 36nMAssay Description:Inhibition of Wistar rat liver cytosol HPPD using HPP as substrate assessed as reduction in O2 consumptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50264337(CHEBI:38321 | MESOTRIONE)
Affinity DataIC50: 37nMAssay Description:Inhibition of Wistar rat liver cytosol HPPD using HPP as substrate assessed as reduction in O2 consumptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50088804(2-[2-nitro-4-(trifluoromethyl)benzoyl]cyclohexane-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of Wistar rat liver cytosol HPPD using HPP as substrate assessed as reduction in O2 consumptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50088804(2-[2-nitro-4-(trifluoromethyl)benzoyl]cyclohexane-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of Wistar rat liver HPPD using 4-Hydroxyphenylpyruvate as substrate assessed as reduction in oxygen consumption preincubated for 3 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Mouse-ear cress)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50056923((9bR)-2,6-diacetyl-3,7,9-trihydroxy-8,9b-dimethyld...)
Affinity DataIC50: 70nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli JM105 using HPPA as substrate after preincubated for 15 min followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50403933(CHEMBL72081)
Affinity DataIC50: 70nMAssay Description:Inhibition of pig liver HPPD using 4-hydroxyphenylpyruvic acid as substrate after 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50403932(CHEMBL308315)
Affinity DataIC50: 110nMAssay Description:Inhibition of pig liver HPPD using 4-hydroxyphenylpyruvic acid as substrate after 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50088793(2-(2-Nitro-benzoyl)-cyclohexane-1,3-dione | CHEMBL...)
Affinity DataIC50: 160nMAssay Description:Inhibition of pig liver HPPD using 4-hydroxyphenylpyruvic acid as substrate after 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Mouse-ear cress)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50075318(2-(2-Chloro-4-methanesulfonyl-benzoyl)-3-hydroxy-c...)
Affinity DataIC50: 250nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli JM105 using 4-HPP as substrate preincubated for 15 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target4-hydroxyphenylpyruvate dioxygenase(Pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50264345(CHEMBL4100001)
Affinity DataIC50: 700nMAssay Description:Inhibition of pig liver HPPD using 4-hydroxyphenylpyruvic acid as substrate after 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Mouse-ear cress)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50264338(CHEMBL4062499)
Affinity DataIC50: 750nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli JM105 using 4-HPP as substrate preincubated for 15 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50264379(CHEMBL4086647)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of pig liver HPPD using HPP as substrate after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Mouse-ear cress)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50264348(CHEMBL4090482)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli JM105 using 4-HPP as substrate preincubated for 15 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50113311(3-Methoxy-2-(2-nitro-benzoyl)-cyclohex-2-enone | C...)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of pig liver HPPD using 4-hydroxyphenylpyruvic acid as substrate after 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50264349(CHEMBL1498742)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of Wistar rat liver cytosol HPPD using HPP as substrate assessed as reduction in O2 consumptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Mouse-ear cress)
University of Siena

Curated by ChEMBL
LigandPNGBDBM26667(CHEMBL399910 | (2S)-5,7-dihydroxy-2-phenyl-3,4-dih...)
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli JM105 using HPPA as substrate after preincubated for 15 min followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50264346(CHEMBL4081042)
Affinity DataIC50: 1.26E+5nMAssay Description:Inhibition of pig liver HPPD using 4-hydroxyphenylpyruvic acid as substrate after 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Mouse-ear cress)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50264305(CHEMBL4102251)
Affinity DataKi:  5nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli BL21(DE3) using HPPA as substrate after 10 mins by UV-Vis spectrometric analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Mouse-ear cress)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50264308(CHEMBL4061385)
Affinity DataKi:  7nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli BL21(DE3) using HPPA as substrate after 10 mins by UV-Vis spectrometric analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Mouse-ear cress)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50264306(CHEMBL4071950)
Affinity DataKi:  7nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli BL21(DE3) using HPPA as substrate after 10 mins by UV-Vis spectrometric analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Mouse-ear cress)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50264374(CHEMBL4069617)
Affinity DataKi:  7nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli BL21(DE3) using HPPA as substrate after 10 mins by UV-Vis spectrometric analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Mouse-ear cress)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50264350(CHEMBL4080249)
Affinity DataKi:  7nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli BL21(DE3) using HPPA as substrate after 10 mins by UV-Vis spectrometric analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Mouse-ear cress)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50264307(CHEMBL4093474)
Affinity DataKi:  7nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli BL21(DE3) using HPPA as substrate after 10 mins by UV-Vis spectrometric analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Mouse-ear cress)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50264309(CHEMBL4060588)
Affinity DataKi:  7nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli BL21(DE3) using HPPA as substrate after 10 mins by UV-Vis spectrometric analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Mouse-ear cress)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50264337(CHEBI:38321 | MESOTRIONE)
Affinity DataKi:  13nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli BL21(DE3) using HPPA as substrate after 10 mins by UV-Vis spectrometric analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Mouse-ear cress)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50264336(TEMBOTRIONE)
Affinity DataKi:  13nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli JM109 using HPPA as substrate after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Mouse-ear cress)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50264333(CHEMBL4082475)
Affinity DataKi:  31nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli JM109 using HPPA as substrate after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Mouse-ear cress)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50264334(CHEMBL4090319)
Affinity DataKi:  31nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli JM109 using HPPA as substrate after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Mouse-ear cress)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50264377(CHEMBL4069274)
Affinity DataKi:  31nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli JM109 using HPPA as substrate after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Mouse-ear cress)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50264335(CHEMBL4080003)
Affinity DataKi:  31nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli JM109 using HPPA as substrate after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed