Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50048985
LigandPNGBDBM50232433(CHEMBL4068514 | US10214537, Example 619)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232438(CHEMBL4100063 | US10214537, Example 256)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM284821(US10023576, Example 11 | 1-((cis)-4-(5-(4-amino-5-...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM284872(US10023576, Example 63 | 7-(2-(4-(oxetan-3-yl)pipe...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232455(CHEMBL4097699 | US10214537, Example 244)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232439(CHEMBL4079663 | US10214537, Example 291)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232457(CHEMBL4091002 | US10214537, Example 225)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232456(CHEMBL4090888 | US10214537, Example 289)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232434(CHEMBL4091410 | US10214537, Example 252)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232452(CHEMBL4070023 | US10214537, Example 229)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232437(CHEMBL4073217 | US10214537, Example 260)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232430(CHEMBL4061855 | US10214537, Example 262)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2:PS as substrate incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232430(CHEMBL4061855 | US10214537, Example 262)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232436(CHEMBL4083625 | US10214537, Example 246)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232451(CHEMBL4064155 | US10214537, Example 267)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232440(CHEMBL4083101 | US10214537, Example 618)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM284871(US10023576, Example 62 | 7-(2-(piperazin-1-yl)pyri...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232445(CHEMBL4062954 | US10214537, Example 290)
Affinity DataIC50: 2nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232444(CHEMBL4071580 | US10214537, Example 288)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232443(CHEMBL4098611 | US10214537, Example 303)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232453(CHEMBL4091906 | US10214537, Example 271)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232444(CHEMBL4071580 | US10214537, Example 288)
Affinity DataIC50: 4nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as suppression of CD69 expression incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232430(CHEMBL4061855 | US10214537, Example 262)
Affinity DataIC50: 4nMAssay Description:Inhibition of PI3Kdelta in mouse spleen assessed suppression of CD86More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232435(CHEMBL4070480)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232450(CHEMBL4099634 | US10214537, Example 266)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232447(CHEMBL4099020)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232446(CHEMBL4098095)
Affinity DataIC50: 5nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232442(CHEMBL4093336 | US10214537, Example 302)
Affinity DataIC50: 5nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM284874(US10023576, Example 65 | 1-(4-(4-(4-amino-5-(1-(te...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232454(CHEMBL4081103 | US10214537, Example 334)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232441(CHEMBL4101075 | US10214537, Example 535)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232431(CHEMBL4087086 | US10214537, Example 263)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232448(CHEMBL4072625)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232449(CHEMBL4072750)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232432(CHEMBL4065659)
Affinity DataIC50: 11nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232430(CHEMBL4061855 | US10214537, Example 262)
Affinity DataIC50: 13nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as suppression of CD69 expression incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232430(CHEMBL4061855 | US10214537, Example 262)
Affinity DataIC50: 24nMAssay Description:Inhibition of PI3Kdelta in BCR-stimulated human B cells assessed as suppression of CD86 expression after 18 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232451(CHEMBL4064155 | US10214537, Example 267)
Affinity DataIC50: 39nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as suppression of CD69 expression incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232430(CHEMBL4061855 | US10214537, Example 262)
Affinity DataIC50: 57nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:PS as substrate incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232444(CHEMBL4071580 | US10214537, Example 288)
Affinity DataIC50: 66nMAssay Description:Inhibition of PI3Kdelta in BCR-stimulated human B cells assessed as suppression of CD86 expression after 18 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232450(CHEMBL4099634 | US10214537, Example 266)
Affinity DataIC50: 81nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as suppression of CD69 expression incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232441(CHEMBL4101075 | US10214537, Example 535)
Affinity DataIC50: 143nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as suppression of CD69 expression incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232449(CHEMBL4072750)
Affinity DataIC50: 193nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as suppression of CD69 expression incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232431(CHEMBL4087086 | US10214537, Example 263)
Affinity DataIC50: 239nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as suppression of CD69 expression incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232453(CHEMBL4091906 | US10214537, Example 271)
Affinity DataIC50: 291nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as suppression of CD69 expression incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232432(CHEMBL4065659)
Affinity DataIC50: 314nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as suppression of CD69 expression incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232442(CHEMBL4093336 | US10214537, Example 302)
Affinity DataIC50: 422nMAssay Description:Inhibition of PI3Kdelta in BCR-stimulated human B cells assessed as suppression of CD86 expression after 18 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232443(CHEMBL4098611 | US10214537, Example 303)
Affinity DataIC50: 681nMAssay Description:Inhibition of PI3Kdelta in BCR-stimulated human B cells assessed as suppression of CD86 expression after 18 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232430(CHEMBL4061855 | US10214537, Example 262)
Affinity DataIC50: 795nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2:PS as substrate incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed
LigandPNGBDBM50232448(CHEMBL4072625)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as suppression of CD69 expression incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2019
Entry Details Article
PubMed