Compile Data Set for Download or QSAR
Report error Found 65 Enz. Inhib. hit(s) with all data for entry = 50048206
LigandPNGBDBM50208168(CHEMBL3924058)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208187(CHEMBL3897116)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208187(CHEMBL3897116)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PI3Kdelta in human THP1 cells assessed as reduction in MCSF-stimulated akt phosphorylation at Thr308 preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208165(CHEMBL3910904)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208173(CHEMBL3980944)
Affinity DataIC50: 3nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208173(CHEMBL3980944)
Affinity DataIC50: 3nMAssay Description:Inhibition of PI3Kdelta in human THP1 cells assessed as reduction in MCSF-stimulated akt phosphorylation at Thr308 preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208188(CHEMBL3985833)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208168(CHEMBL3924058)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of PI3Kdelta in human THP1 cells assessed as reduction in MCSF-stimulated akt phosphorylation at Thr308 preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208164(CHEMBL3928750)
Affinity DataIC50: 4nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208172(CHEMBL3901256)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208166(CHEMBL3901527)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50208165(CHEMBL3910904)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of PI3Kdelta in human THP1 cells assessed as reduction in MCSF-stimulated akt phosphorylation at Thr308 preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208176(CHEMBL3976777)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208166(CHEMBL3901527)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of PI3Kdelta in human THP1 cells assessed as reduction in MCSF-stimulated akt phosphorylation at Thr308 preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50208167(CHEMBL3985921)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208188(CHEMBL3985833)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of PI3Kdelta in human THP1 cells assessed as reduction in MCSF-stimulated akt phosphorylation at Thr308 preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208176(CHEMBL3976777)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of PI3Kdelta in human THP1 cells assessed as reduction in MCSF-stimulated akt phosphorylation at Thr308 preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208192(CHEMBL3957154)
Affinity DataIC50: 7nMAssay Description:Inhibition of PI3Kdelta in human THP1 cells assessed as reduction in MCSF-stimulated akt phosphorylation at Thr308 preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208165(CHEMBL3910904)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of PI3Kdelta in human THP1 cells assessed as reduction in MCSF-stimulated akt phosphorylation at Thr308 preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208181(CHEMBL3963227)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208170(CHEMBL3902629)
Affinity DataIC50: 9nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208192(CHEMBL3957154)
Affinity DataIC50: 10nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208164(CHEMBL3928750)
Affinity DataIC50: 11nMAssay Description:Inhibition of PI3Kdelta in human THP1 cells assessed as reduction in MCSF-stimulated akt phosphorylation at Thr308 preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208186(CHEMBL3957244)
Affinity DataIC50: 11nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208181(CHEMBL3963227)
Affinity DataIC50: 11nMAssay Description:Inhibition of PI3Kdelta in human THP1 cells assessed as reduction in MCSF-stimulated akt phosphorylation at Thr308 preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208180(CHEMBL3934713)
Affinity DataIC50: 12nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208171(CHEMBL3898391)
Affinity DataIC50: 13nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208167(CHEMBL3985921)
Affinity DataIC50: 16nMAssay Description:Inhibition of PI3Kdelta in human THP1 cells assessed as reduction in MCSF-stimulated akt phosphorylation at Thr308 preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208178(CHEMBL3925368)
Affinity DataIC50: 17nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208186(CHEMBL3957244)
Affinity DataIC50: 18nMAssay Description:Inhibition of PI3Kdelta in human THP1 cells assessed as reduction in MCSF-stimulated akt phosphorylation at Thr308 preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208163(CHEMBL3899628)
Affinity DataIC50: 25nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208185(CHEMBL3906055)
Affinity DataIC50: 31nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208172(CHEMBL3901256)
Affinity DataIC50: 35nMAssay Description:Inhibition of PI3Kdelta in human THP1 cells assessed as reduction in MCSF-stimulated akt phosphorylation at Thr308 preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208165(CHEMBL3910904)
Affinity DataIC50: 47nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as reduction in anti-IgD-mediated B-cell activation by measuring decrease in CD19+ cells expres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208170(CHEMBL3902629)
Affinity DataIC50: 47nMAssay Description:Inhibition of PI3Kdelta in human THP1 cells assessed as reduction in MCSF-stimulated akt phosphorylation at Thr308 preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208178(CHEMBL3925368)
Affinity DataIC50: 51nMAssay Description:Inhibition of PI3Kdelta in human THP1 cells assessed as reduction in MCSF-stimulated akt phosphorylation at Thr308 preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208171(CHEMBL3898391)
Affinity DataIC50: 51nMAssay Description:Inhibition of PI3Kdelta in human THP1 cells assessed as reduction in MCSF-stimulated akt phosphorylation at Thr308 preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208175(CHEMBL3981636)
Affinity DataIC50: 52nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208169(CHEMBL3986289)
Affinity DataIC50: 57nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208190(CHEMBL3911640)
Affinity DataIC50: 60nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208182(CHEMBL3900775)
Affinity DataIC50: 71nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208165(CHEMBL3910904)
Affinity DataIC50: 72nMAssay Description:Inhibition of N-terminal His-tagged full length recombinant human PI3K p110gamma expressed in baculovirus expression system using PIP2 as substrate p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208177(CHEMBL3973614)
Affinity DataIC50: 73nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208174(CHEMBL3918777)
Affinity DataIC50: 75nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208191(CHEMBL3920579)
Affinity DataIC50: 76nMAssay Description:Inhibition of PI3Kdelta in human THP1 cells assessed as reduction in MCSF-stimulated akt phosphorylation at Thr308 preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208191(CHEMBL3920579)
Affinity DataIC50: 91nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208165(CHEMBL3910904)
Affinity DataIC50: 94nMAssay Description:Inhibition of full length recombinant human N-terminal Hi6s-tagged PI3K p110beta/full length human p85alpha expressed in baculovirus infected Sf21 in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50208184(CHEMBL3946603)
Affinity DataIC50: 110nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50323726(2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tol...)
Affinity DataIC50: 130nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50208175(CHEMBL3981636)
Affinity DataIC50: 150nMAssay Description:Inhibition of PI3Kdelta in human THP1 cells assessed as reduction in MCSF-stimulated akt phosphorylation at Thr308 preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
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