Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50049020
TargetBone morphogenetic protein receptor type-1B(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50262079(LDN-193189 | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo...)
Affinity DataIC50: 0.940nMAssay Description:Inhibition of human ALK6 using casein as substrate in presence of 10 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 3(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50413752(L-783277 | CHEMBL2012519)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human FLT4 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50413752(L-783277 | CHEMBL2012519)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK peptide as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50262079(LDN-193189 | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human ALK3 using casein as substrate in presence of 10 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetActivin receptor type-1(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50262079(LDN-193189 | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 2(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50413752(L-783277 | CHEMBL2012519)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human KDR using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
LigandPNGBDBM50413752(L-783277 | CHEMBL2012519)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human MEK2 using ERK2 as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50262079(LDN-193189 | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human ALK1 using casein as substrate in presence of 10 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTGF-beta receptor type-1(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50262079(LDN-193189 | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo...)
Affinity DataIC50: 27nMAssay Description:Inhibition of human ALK5 using casein as substrate in presence of 10 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetActivin receptor type-1B(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50262079(LDN-193189 | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo...)
Affinity DataIC50: 43nMAssay Description:Inhibition of human ALK4 using casein as substrate in presence of 10 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50232968(CHEMBL4099337)
Affinity DataIC50: 62nMAssay Description:Inhibition of human ALK1 using casein as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50232968(CHEMBL4099337)
Affinity DataIC50: 62nMAssay Description:Inhibition of human ALK1 using casein as substrate in presence of 10 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50232968(CHEMBL4099337)
Affinity DataIC50: 115nMAssay Description:Inhibition of human FLT4 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50413752(L-783277 | CHEMBL2012519)
Affinity DataIC50: 125nMAssay Description:Inhibition of human ALK1 using casein as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50232968(CHEMBL4099337)
Affinity DataIC50: 163nMAssay Description:Inhibition of human KDR using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
LigandPNGBDBM50232968(CHEMBL4099337)
Affinity DataIC50: 187nMAssay Description:Inhibition of human MEK2 using ERK2 as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50232968(CHEMBL4099337)
Affinity DataIC50: 188nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK peptide as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetActivin receptor type-1(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50232968(CHEMBL4099337)
Affinity DataIC50: 217nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
LigandPNGBDBM50413752(L-783277 | CHEMBL2012519)
Affinity DataIC50: 388nMAssay Description:Inhibition of human MKK6 using p38a as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-1B(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50232968(CHEMBL4099337)
Affinity DataIC50: 727nMAssay Description:Inhibition of human ALK6 using casein as substrate in presence of 10 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50232970(CHEMBL4061009)
Affinity DataIC50: 770nMAssay Description:Inhibition of human ALK1 using casein as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50232968(CHEMBL4099337)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of human ALK1 using casein as substrate in presence of 200 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50232971(CHEMBL4082892)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human ALK1 using casein as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50232969(CHEMBL4072401)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of human ALK1 using casein as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetActivin receptor type-1B(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50232968(CHEMBL4099337)
Affinity DataIC50: 2.76E+3nMAssay Description:Inhibition of human ALK4 using casein as substrate in presence of 10 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetActivin receptor type-1(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50232968(CHEMBL4099337)
Affinity DataIC50: 3.35E+3nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 200 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50232968(CHEMBL4099337)
Affinity DataIC50: 6.27E+3nMAssay Description:Inhibition of human ALK3 using casein as substrate in presence of 10 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50232968(CHEMBL4099337)
Affinity DataIC50: 7.21E+3nMAssay Description:Inhibition of human ALK5 using casein as substrate in presence of 10 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
LigandPNGBDBM50232968(CHEMBL4099337)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MKK6 using p38a as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed