Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50049011
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Siberian Branch of The Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50232848(CHEMBL4084310)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Siberian Branch of The Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50232847(CHEMBL4090202)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Siberian Branch of The Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50232843(CHEMBL2207624)
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Siberian Branch of The Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50232845(CHEMBL2207625)
Affinity DataIC50: 570nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Siberian Branch of The Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50232846(CHEMBL4069136)
Affinity DataIC50: 750nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Siberian Branch of The Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50232849(CHEMBL4102274)
Affinity DataIC50: 790nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Siberian Branch of The Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50232836(CHEMBL2207621)
Affinity DataIC50: 940nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Siberian Branch of The Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50232838(CHEMBL4068083)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Siberian Branch of The Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50232850(CHEMBL4069754)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Siberian Branch of The Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50232837(CHEMBL2207620)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Siberian Branch of The Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50232851(CHEMBL2207623)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Siberian Branch of The Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50232844(CHEMBL2207622)
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Siberian Branch of The Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50232835(CHEMBL4063265)
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Siberian Branch of The Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50232843(CHEMBL2207624)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) assessed as reduction in BHQ1 excision from 3'-end of [32P]-labeled oligonucleotide substrate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Siberian Branch of The Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50232841(CHEBI:122 | (+)-Usnic Acid | (-)-Usnic Acid)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Siberian Branch of The Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50056923((9bR)-2,6-diacetyl-3,7,9-trihydroxy-8,9b-dimethyld...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Siberian Branch of The Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50232840(CHEMBL4087033)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Siberian Branch of The Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50232839(CHEMBL4104897)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed