Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50000731
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259802(CHEMBL4071284)
Affinity DataEC50:  590nMAssay Description:Inhibition of BACE1 in human H4 cells expressing human APP K595N/M596L double mutant assessed as decrease in amyloid beta 42 and amyloid beta 40 leve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259803(CHEMBL4093064)
Affinity DataEC50:  480nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259800(CHEMBL4062635)
Affinity DataEC50:  1.21E+3nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259804(CHEMBL4075051)
Affinity DataEC50:  350nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259805(CHEMBL4065393)
Affinity DataEC50:  880nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259801(CHEMBL4092083)
Affinity DataEC50:  1.33E+3nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259797(CHEMBL4074001)
Affinity DataEC50:  410nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259806(CHEMBL4100768)
Affinity DataEC50:  810nMAssay Description:Inhibition of BACE1 in human H4 cells expressing human APP K595N/M596L double mutant assessed as decrease in amyloid beta 42 and amyloid beta 40 leve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259799(CHEMBL4078427)
Affinity DataEC50:  290nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259798(CHEMBL4095483)
Affinity DataEC50:  670nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259806(CHEMBL4100768)
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259804(CHEMBL4075051)
Affinity DataIC50: 85nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259801(CHEMBL4092083)
Affinity DataIC50: 98nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259800(CHEMBL4062635)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259799(CHEMBL4078427)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259797(CHEMBL4074001)
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259798(CHEMBL4095483)
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259803(CHEMBL4093064)
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259805(CHEMBL4065393)
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259802(CHEMBL4071284)
Affinity DataIC50: 660nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2020
Entry Details Article
PubMed