Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50047838
TargetE3 ubiquitin-protein ligase SMURF1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM239101(US9403810, 2.2 | US10195181, Example 2.2)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of N-terminal Prolabel-tagged human Smurf-1 HECT domain expressed in HEK293 cells assessed as accumulation of Smurf-1 protein using chemil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2018
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase SMURF1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50193010(CHEMBL3949800)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of N-terminal Prolabel-tagged human Smurf-1 HECT domain expressed in HEK293 cells assessed as accumulation of Smurf-1 protein using chemil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2018
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase SMURF1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM239094(US9403810, 1.3 | US10195181, Example 1.3)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of N-terminal Prolabel-tagged human Smurf-1 HECT domain expressed in HEK293 cells assessed as accumulation of Smurf-1 protein using chemil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2018
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase SMURF1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50193011(CHEMBL3945602)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of N-terminal Prolabel-tagged human Smurf-1 HECT domain expressed in HEK293 cells assessed as accumulation of Smurf-1 protein using chemil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2018
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase SMURF1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM239105(US9403810, 6 | US10195181, Example 6)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of N-terminal Prolabel-tagged human Smurf-1 HECT domain expressed in HEK293 cells assessed as accumulation of Smurf-1 protein using chemil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2018
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase SMURF1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM239114(US9403810, 14)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of N-terminal Prolabel-tagged human Smurf-1 HECT domain expressed in HEK293 cells assessed as accumulation of Smurf-1 protein using chemil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2018
Entry Details Article
PubMed