Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 7502
TargetProstaglandin G/H synthase 2(Sheep)
Indian Institute of Technology (Banaras Hindu University)

LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 540nMAssay Description:The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Indian Institute of Technology (Banaras Hindu University)

LigandPNGBDBM198173(2-((5-(4-Nitrophenylamino)-1,3,4-oxadiazol-2-yl)me...)
Affinity DataIC50: 600nMAssay Description:The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Indian Institute of Technology (Banaras Hindu University)

LigandPNGBDBM198172(2-((5-(4-Chlorophenylamino)-1,3,4-oxadiazol-2-yl)m...)
Affinity DataIC50: 650nMAssay Description:The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Indian Institute of Technology (Banaras Hindu University)

LigandPNGBDBM198171(2-((5-(4-Methoxyphenylamino)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50: 770nMAssay Description:The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Indian Institute of Technology (Banaras Hindu University)

LigandPNGBDBM198174(2-((5-(4-Methoxyphenylamino)-1,3,4-thiadiazol-2-yl...)
Affinity DataIC50: 900nMAssay Description:The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Indian Institute of Technology (Banaras Hindu University)

LigandPNGBDBM198176(2-((5-(4-Nitrophenylamino)-1,3,4-thiadiazol-2-yl)m...)
Affinity DataIC50: 1.01E+3nMAssay Description:The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Indian Institute of Technology (Banaras Hindu University)

LigandPNGBDBM198175(2-((5-(4-Chlorophenylamino)-1,3,4-thiadiazol-2-yl)...)
Affinity DataIC50: 1.11E+3nMAssay Description:The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Indian Institute of Technology (Banaras Hindu University)

LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 3.67E+3nMAssay Description:The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Sheep)
Indian Institute of Technology (Banaras Hindu University)

LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 3.79E+3nMAssay Description:The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Indian Institute of Technology (Banaras Hindu University)

LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 5.83E+4nMAssay Description:The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Indian Institute of Technology (Banaras Hindu University)

LigandPNGBDBM198174(2-((5-(4-Methoxyphenylamino)-1,3,4-thiadiazol-2-yl...)
Affinity DataIC50: 6.01E+4nMAssay Description:The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Indian Institute of Technology (Banaras Hindu University)

LigandPNGBDBM198171(2-((5-(4-Methoxyphenylamino)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50: 6.05E+4nMAssay Description:The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Indian Institute of Technology (Banaras Hindu University)

LigandPNGBDBM198175(2-((5-(4-Chlorophenylamino)-1,3,4-thiadiazol-2-yl)...)
Affinity DataIC50: 6.22E+4nMAssay Description:The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Indian Institute of Technology (Banaras Hindu University)

LigandPNGBDBM198173(2-((5-(4-Nitrophenylamino)-1,3,4-oxadiazol-2-yl)me...)
Affinity DataIC50: 6.24E+4nMAssay Description:The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Indian Institute of Technology (Banaras Hindu University)

LigandPNGBDBM198176(2-((5-(4-Nitrophenylamino)-1,3,4-thiadiazol-2-yl)m...)
Affinity DataIC50: 6.32E+4nMAssay Description:The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Indian Institute of Technology (Banaras Hindu University)

LigandPNGBDBM198172(2-((5-(4-Chlorophenylamino)-1,3,4-oxadiazol-2-yl)m...)
Affinity DataIC50: 6.45E+4nMAssay Description:The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Indian Institute of Technology (Banaras Hindu University)

LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataKi:  490nMAssay Description:The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Indian Institute of Technology (Banaras Hindu University)

LigandPNGBDBM198173(2-((5-(4-Nitrophenylamino)-1,3,4-oxadiazol-2-yl)me...)
Affinity DataKi:  500nMAssay Description:The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Indian Institute of Technology (Banaras Hindu University)

LigandPNGBDBM198172(2-((5-(4-Chlorophenylamino)-1,3,4-oxadiazol-2-yl)m...)
Affinity DataKi:  630nMAssay Description:The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Indian Institute of Technology (Banaras Hindu University)

LigandPNGBDBM198171(2-((5-(4-Methoxyphenylamino)-1,3,4-oxadiazol-2-yl)...)
Affinity DataKi:  650nMAssay Description:The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Indian Institute of Technology (Banaras Hindu University)

LigandPNGBDBM198174(2-((5-(4-Methoxyphenylamino)-1,3,4-thiadiazol-2-yl...)
Affinity DataKi:  770nMAssay Description:The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Indian Institute of Technology (Banaras Hindu University)

LigandPNGBDBM198176(2-((5-(4-Nitrophenylamino)-1,3,4-thiadiazol-2-yl)m...)
Affinity DataKi:  880nMAssay Description:The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Indian Institute of Technology (Banaras Hindu University)

LigandPNGBDBM198175(2-((5-(4-Chlorophenylamino)-1,3,4-thiadiazol-2-yl)...)
Affinity DataKi:  960nMAssay Description:The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed