Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50048260
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50004058(N-(butylsulfonyl)-O-(4-piperidin-4-ylbutyl)-L-tyro...)
Affinity DataIC50: 40nMAssay Description:Displacement of fibrinogen from human platelet GP2b/GP3a receptor after 2 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210630(CHEMBL3929796)
Affinity DataIC50: 80nMAssay Description:Displacement of fibrinogen from human platelet GP2b/GP3a receptor after 2 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50004058(N-(butylsulfonyl)-O-(4-piperidin-4-ylbutyl)-L-tyro...)
Affinity DataIC50: 90nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210630(CHEMBL3929796)
Affinity DataIC50: 180nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210673(CHEMBL3902930)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210680(CHEMBL3946875)
Affinity DataIC50: 280nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210688(CHEMBL3913603)
Affinity DataIC50: 370nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210686(CHEMBL3956721)
Affinity DataIC50: 520nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210630(CHEMBL3929796)
Affinity DataIC50: 530nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of thrombin-induced platelet aggregation preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210676(CHEMBL3895541)
Affinity DataIC50: 840nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210630(CHEMBL3929796)
Affinity DataIC50: 1.01E+3nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of U46619-induced platelet aggregation preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210689(CHEMBL3977308)
Affinity DataIC50: 1.08E+3nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210630(CHEMBL3929796)
Affinity DataIC50: 1.32E+3nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210676(CHEMBL3895541)
Affinity DataIC50: 1.33E+3nMAssay Description:Displacement of fibrinogen from human platelet GP2b/GP3a receptor after 2 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210679(CHEMBL3973895)
Affinity DataIC50: 1.65E+3nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210631(CHEMBL3968819)
Affinity DataIC50: 2.10E+3nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210677(CHEMBL3948531)
Affinity DataIC50: 3.29E+3nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210674(CHEMBL3970157)
Affinity DataIC50: 3.40E+3nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210678(CHEMBL3923533)
Affinity DataIC50: 4.01E+3nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210629(CHEMBL3892875)
Affinity DataIC50: 5.40E+3nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210682(CHEMBL3892855)
Affinity DataIC50: 6.38E+3nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210691(CHEMBL3910876)
Affinity DataIC50: 7.60E+3nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210683(CHEMBL3904616)
Affinity DataIC50: 7.90E+3nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210681(CHEMBL3971219)
Affinity DataIC50: 1.27E+4nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210675(CHEMBL3983425)
Affinity DataIC50: 1.28E+4nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210687(CHEMBL3910084)
Affinity DataIC50: 1.88E+4nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210676(CHEMBL3895541)
Affinity DataIC50: 2.29E+4nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of thrombin-induced platelet aggregation preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210676(CHEMBL3895541)
Affinity DataIC50: 2.36E+4nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of U46619-induced platelet aggregation preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210632(CHEMBL3947602)
Affinity DataIC50: 2.46E+4nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210676(CHEMBL3895541)
Affinity DataIC50: 2.77E+4nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210685(CHEMBL3922603)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210684(CHEMBL3894590)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210690(CHEMBL3931514)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2018
Entry Details Article
PubMed