Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50047832
TargetCoagulation factor VII/Tissue factor(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192770(CHEMBL3956096)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of recombinant human TF-factor 7a using factor 10 as substrate at 37 degCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor VII/Tissue factor(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192768(CHEMBL3900166)
Affinity DataKi:  0.140nMAssay Description:Inhibition of recombinant human TF-factor 7a using factor 10 as substrate at 37 degCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor VII/Tissue factor(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM189445(US9174974, Example 31)
Affinity DataKi:  0.160nMAssay Description:Inhibition of human TF-factor 7a (366 to 11 residues) using factor 10 as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetCoagulation factor VII/Tissue factor(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192767(CHEMBL3984725)
Affinity DataKi:  0.220nMAssay Description:Inhibition of recombinant human TF-factor 7a using factor 10 as substrate at 37 degCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetCoagulation factor VII/Tissue factor(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192771(CHEMBL3898371)
Affinity DataKi:  0.550nMAssay Description:Inhibition of recombinant human TF-factor 7a using factor 10 as substrate at 37 degCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetCoagulation factor VII/Tissue factor(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192766(CHEMBL3967204)
Affinity DataKi:  0.720nMAssay Description:Inhibition of recombinant human TF-factor 7a using factor 10 as substrate at 37 degCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetCoagulation factor VII/Tissue factor(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192769(CHEMBL3976650)
Affinity DataKi:  2nMAssay Description:Inhibition of human TF-factor 7a (366 to 11 residues) using factor 10 as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetCoagulation factor VII/Tissue factor(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192765(CHEMBL3895930)
Affinity DataKi:  4.40nMAssay Description:Inhibition of recombinant human TF-factor 7a using factor 10 as substrate at 37 degCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192764(CHEMBL3934882)
Affinity DataKi:  15nMAssay Description:Inhibition of human kallikrein1 at 37 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetCoagulation factor VII/Tissue factor(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192764(CHEMBL3934882)
Affinity DataKi:  18nMAssay Description:Inhibition of recombinant human TF-factor 7a using factor 10 as substrate at 37 degCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192771(CHEMBL3898371)
Affinity DataKi:  70nMAssay Description:Inhibition of activated protein C (unknown origin) at 37 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192770(CHEMBL3956096)
Affinity DataKi:  155nMAssay Description:Inhibition of activated protein C (unknown origin) at 37 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192766(CHEMBL3967204)
Affinity DataKi:  175nMAssay Description:Inhibition of activated protein C (unknown origin) at 37 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192764(CHEMBL3934882)
Affinity DataKi:  220nMAssay Description:Inhibition of activated protein C (unknown origin) at 37 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192767(CHEMBL3984725)
Affinity DataKi:  340nMAssay Description:Inhibition of activated protein C (unknown origin) at 37 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192768(CHEMBL3900166)
Affinity DataKi:  725nMAssay Description:Inhibition of activated protein C (unknown origin) at 37 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192768(CHEMBL3900166)
Affinity DataKi:  850nMAssay Description:Inhibition of factor 10a (unknown origin) at 25 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192770(CHEMBL3956096)
Affinity DataKi:  900nMAssay Description:Inhibition of factor 10a (unknown origin) at 25 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192766(CHEMBL3967204)
Affinity DataKi:  960nMAssay Description:Inhibition of human kallikrein1 at 37 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192766(CHEMBL3967204)
Affinity DataKi:  1.05E+3nMAssay Description:Inhibition of factor 10a (unknown origin) at 25 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192771(CHEMBL3898371)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of human kallikrein1 at 37 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192768(CHEMBL3900166)
Affinity DataKi:  1.15E+3nMAssay Description:Inhibition of human kallikrein1 at 37 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192770(CHEMBL3956096)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human kallikrein1 at 37 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192765(CHEMBL3895930)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of factor 10a (unknown origin) at 25 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192765(CHEMBL3895930)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of activated protein C (unknown origin) at 37 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192767(CHEMBL3984725)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of human kallikrein1 at 37 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192767(CHEMBL3984725)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of factor 10a (unknown origin) at 25 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192764(CHEMBL3934882)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of factor 10a (unknown origin) at 25 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192765(CHEMBL3895930)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibition of human kallikrein1 at 37 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192771(CHEMBL3898371)
Affinity DataKi:  6.65E+3nMAssay Description:Inhibition of factor 10a (unknown origin) at 25 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192771(CHEMBL3898371)
Affinity DataKi: >1.33E+4nMAssay Description:Inhibition of thrombin (unknown origin) at 25 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192770(CHEMBL3956096)
Affinity DataKi: >1.33E+4nMAssay Description:Inhibition of thrombin (unknown origin) at 25 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192765(CHEMBL3895930)
Affinity DataKi: >1.33E+4nMAssay Description:Inhibition of thrombin (unknown origin) at 25 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192766(CHEMBL3967204)
Affinity DataKi: >1.33E+4nMAssay Description:Inhibition of thrombin (unknown origin) at 25 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192767(CHEMBL3984725)
Affinity DataKi: >1.33E+4nMAssay Description:Inhibition of thrombin (unknown origin) at 25 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192768(CHEMBL3900166)
Affinity DataKi: >1.33E+4nMAssay Description:Inhibition of thrombin (unknown origin) at 25 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50192764(CHEMBL3934882)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of thrombin (unknown origin) at 25 degC by chromogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed