Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50009970
TargetMu-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM21008((4S,7S,13S)-13-[(2S)-2-amino-3-(4-hydroxyphenyl)pr...)
Affinity DataIC50: 1.60nMAssay Description:Agonist activity at human MOR expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation by EIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM21008((4S,7S,13S)-13-[(2S)-2-amino-3-(4-hydroxyphenyl)pr...)
Affinity DataIC50: 1.60nMAssay Description:Agonist activity at human DOR expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation by EIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataIC50: 4.30nMAssay Description:Agonist activity at human MOR expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation by EIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50533843(CHEMBL4469560)
Affinity DataIC50: 6.10nMAssay Description:Agonist activity at human MOR expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation by EIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataIC50: 19nMAssay Description:Agonist activity at human MOR expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation by EIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50268462(c[L-Phe-D-pro-L-Phe-L-trp] | CHEMBL506616)
Affinity DataIC50: 47nMAssay Description:Binding affinity to KOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50533844(CHEMBL4513822)
Affinity DataIC50: 183nMAssay Description:Agonist activity at human MOR expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation by EIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50268462(c[L-Phe-D-pro-L-Phe-L-trp] | CHEMBL506616)
Affinity DataIC50: 260nMAssay Description:Binding affinity to MOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50268462(c[L-Phe-D-pro-L-Phe-L-trp] | CHEMBL506616)
Affinity DataIC50: 2.60E+3nMAssay Description:Binding affinity to DOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50533844(CHEMBL4513822)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM21008((4S,7S,13S)-13-[(2S)-2-amino-3-(4-hydroxyphenyl)pr...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50533843(CHEMBL4469560)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50268462(c[L-Phe-D-pro-L-Phe-L-trp] | CHEMBL506616)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50268462(c[L-Phe-D-pro-L-Phe-L-trp] | CHEMBL506616)
Affinity DataKi:  127nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50533843(CHEMBL4469560)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50533846(CHEMBL4581101)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50533845(CHEMBL4580409)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50533842(CHEMBL4543931)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50533845(CHEMBL4580409)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50533846(CHEMBL4581101)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50533847(CHEMBL4446555)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50533842(CHEMBL4543931)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50533843(CHEMBL4469560)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50533847(CHEMBL4446555)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50533846(CHEMBL4581101)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50533845(CHEMBL4580409)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50533844(CHEMBL4513822)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50268462(c[L-Phe-D-pro-L-Phe-L-trp] | CHEMBL506616)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50533842(CHEMBL4543931)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed