Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50010091
TargetProstaglandin G/H synthase 2(Human)
American University of Madaba

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human COX2 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
American University of Madaba

Curated by ChEMBL
LigandPNGBDBM50535062(CHEMBL4563498)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human COX2 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
American University of Madaba

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of ovine COX1 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measured after 2 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
American University of Madaba

Curated by ChEMBL
LigandPNGBDBM50535066(CHEMBL4461324)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of ovine COX1 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measured after 2 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
American University of Madaba

Curated by ChEMBL
LigandPNGBDBM50535064(CHEMBL4588254)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of ovine COX1 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measured after 2 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
American University of Madaba

Curated by ChEMBL
LigandPNGBDBM50535064(CHEMBL4588254)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of recombinant human COX2 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
American University of Madaba

Curated by ChEMBL
LigandPNGBDBM50535068(CHEMBL4471266)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of recombinant human COX2 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
American University of Madaba

Curated by ChEMBL
LigandPNGBDBM50535061(CHEMBL4538175)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of recombinant human COX2 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
American University of Madaba

Curated by ChEMBL
LigandPNGBDBM50535060(CHEMBL4461039)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of ovine COX1 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measured after 2 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
American University of Madaba

Curated by ChEMBL
LigandPNGBDBM50535063(CHEMBL4559331)
Affinity DataIC50: 9.90E+4nMAssay Description:Inhibition of recombinant human COX2 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
American University of Madaba

Curated by ChEMBL
LigandPNGBDBM50535065(CHEMBL4528204)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ovine COX1 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measured after 2 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
American University of Madaba

Curated by ChEMBL
LigandPNGBDBM50535060(CHEMBL4461039)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant human COX2 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
American University of Madaba

Curated by ChEMBL
LigandPNGBDBM50535068(CHEMBL4471266)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of ovine COX1 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measured after 2 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
American University of Madaba

Curated by ChEMBL
LigandPNGBDBM50535063(CHEMBL4559331)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of ovine COX1 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measured after 2 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
American University of Madaba

Curated by ChEMBL
LigandPNGBDBM50535062(CHEMBL4563498)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of ovine COX1 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measured after 2 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
American University of Madaba

Curated by ChEMBL
LigandPNGBDBM50535067(CHEMBL4468689)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of recombinant human COX2 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
American University of Madaba

Curated by ChEMBL
LigandPNGBDBM50535066(CHEMBL4461324)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of recombinant human COX2 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
American University of Madaba

Curated by ChEMBL
LigandPNGBDBM50535061(CHEMBL4538175)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of ovine COX1 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measured after 2 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
American University of Madaba

Curated by ChEMBL
LigandPNGBDBM50535067(CHEMBL4468689)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of ovine COX1 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measured after 2 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
American University of Madaba

Curated by ChEMBL
LigandPNGBDBM50535065(CHEMBL4528204)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of recombinant human COX2 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed