Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50001846
TargetDihydrofolate reductase(Escherichia coli)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018477(CHEMBL278345 | 5-(3,4-Dimethoxy-5-propyl-benzyl)-p...)
Affinity DataKi:  0.400nMAssay Description:Antibacterial activity against Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018478(CHEMBL23609 | TCMDC-137664 | 5-(3-Ethoxy-4,5-dimet...)
Affinity DataKi:  0.5nMAssay Description:Antibacterial activity against Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018473(CHEMBL59416 | 2-Allyl-4-(2,4-diamino-pyrimidin-5-y...)
Affinity DataKi:  0.800nMAssay Description:Antibacterial activity against Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018469(CHEMBL301030 | 5-(4-Methoxy-3,5-dipropenyl-benzyl)...)
Affinity DataKi:  0.800nMAssay Description:Antibacterial activity against Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018472(CHEMBL23338 | 5-(3,4-Dimethoxy-5-propenyl-benzyl)-...)
Affinity DataKi:  0.900nMAssay Description:Antibacterial activity against Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018475(CHEMBL60069 | 5-(3,4-Dimethoxy-5-propoxy-benzyl)-p...)
Affinity DataKi:  1nMAssay Description:Antibacterial activity against Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataKi:  1.30nMAssay Description:Antibacterial activity against Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018472(CHEMBL23338 | 5-(3,4-Dimethoxy-5-propenyl-benzyl)-...)
Affinity DataKi:  1.40nMAssay Description:Antibacterial activity against Staphylococcus aureus DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018475(CHEMBL60069 | 5-(3,4-Dimethoxy-5-propoxy-benzyl)-p...)
Affinity DataKi:  1.40nMAssay Description:Antibacterial activity against Staphylococcus aureus DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018479(CHEMBL58550 | 5-(3-Allyl-4-methoxy-5-propyl-benzyl...)
Affinity DataKi:  1.60nMAssay Description:Antibacterial activity against Escherichia coli DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018474(CHEMBL23746 | 4-(2,4-Diamino-pyrimidin-5-ylmethyl)...)
Affinity DataKi:  1.70nMAssay Description:Antibacterial activity against Escherichia coli DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018470(CHEMBL282022 | 5-(3-Allyl-4,5-dimethoxy-benzyl)-py...)
Affinity DataKi:  1.80nMAssay Description:Antibacterial activity against Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018471(CHEMBL301236 | 5-(3,5-Diallyl-4-methoxy-benzyl)-py...)
Affinity DataKi:  2.10nMAssay Description:Antibacterial activity against Staphylococcus aureus DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018478(CHEMBL23609 | TCMDC-137664 | 5-(3-Ethoxy-4,5-dimet...)
Affinity DataKi:  2.5nMAssay Description:Antibacterial activity against Staphylococcus aureus DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018470(CHEMBL282022 | 5-(3-Allyl-4,5-dimethoxy-benzyl)-py...)
Affinity DataKi:  2.80nMAssay Description:Antibacterial activity against Staphylococcus aureus DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018476(CHEMBL59946 | 5-(3-Allyloxy-4,5-dimethoxy-benzyl)-...)
Affinity DataKi:  3nMAssay Description:Antibacterial activity against Staphylococcus aureusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018480(CHEMBL26337 | 5-(4-Methoxy-3,5-dipropyl-benzyl)-py...)
Affinity DataKi:  3.20nMAssay Description:Antibacterial activity against Staphylococcus aureusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataKi:  5.10nMAssay Description:Antibacterial activity against Staphylococcus aureus DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)