Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 1151
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9349((2Z)-but-2-enedioic acid; 9-amino-6-chloro-1,2,3,4...)
Affinity DataIC50: 11.7nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9352(9-amino-6-fluoro-1,2,3,4-tetrahydroacridin-1-ol | ...)
Affinity DataIC50: 292nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 319nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9381(6-chloro-9-{[(4-fluorophenyl)methyl]amino}-1,2,3,4...)
Affinity DataIC50: 823nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9380(9-(benzylamino)-6-chloro-1,2,3,4-tetrahydroacridin...)
Affinity DataIC50: 1.30E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9354(9-(methylamino)-1,2,3,4-tetrahydroacridin-1-ol | 9...)
Affinity DataIC50: 1.76E+3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9351(9-amino-6-(trifluoromethyl)-1,2,3,4-tetrahydroacri...)
Affinity DataIC50: 1.77E+3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9350((2Z)-but-2-enedioic acid; 9-amino-6-methoxy-1,2,3,...)
Affinity DataIC50: 2.00E+3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9357((2Z)-but-2-enedioic acid; 9-[(2-phenylethyl)amino]...)
Affinity DataIC50: 3.39E+3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9358(9-[(3-phenoxypropyl)amino]-1,2,3,4-tetrahydroacrid...)
Affinity DataIC50: 3.98E+3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9347(9-amino-1,2,3,4-tetrahydroacridin-1-ol maleate | C...)
Affinity DataIC50: 4.00E+3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9372(9-{[(2-methylphenyl)methyl]amino}-1,2,3,4-tetrahyd...)
Affinity DataIC50: 5.89E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9353((2Z)-but-2-enedioic acid; 9-amino-1H,2H,3H-cyclope...)
Affinity DataIC50: 5.97E+3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9356(9-{[2-(dimethylamino)ethyl]amino}-1,2,3,4-tetrahyd...)
Affinity DataIC50: 7.68E+3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9382(9-(benzylamino)-6-fluoro-1,2,3,4-tetrahydroacridin...)
Affinity DataIC50: 8.63E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9363(9-{[(2-chlorophenyl)methyl]amino}-1,2,3,4-tetrahyd...)
Affinity DataIC50: 1.03E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9371(9-{[(4-methoxyphenyl)methyl]amino}-1,2,3,4-tetrahy...)
Affinity DataIC50: 1.09E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9378((2E)-but-2-enedioic acid; 9-{[(2,3,4,5,6-pentafluo...)
Affinity DataIC50: 1.26E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9367(9-{[(3-fluorophenyl)methyl]amino}-1,2,3,4-tetrahyd...)
Affinity DataIC50: 1.31E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9355(9-(propylamino)-1,2,3,4-tetrahydroacridin-1-ol | 9...)
Affinity DataIC50: 1.33E+4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9364(9-{[(3-chlorophenyl)methyl]amino}-1,2,3,4-tetrahyd...)
Affinity DataIC50: 1.33E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9375(9-({[2-(trifluoromethyl)phenyl]methyl}amino)-1,2,3...)
Affinity DataIC50: 1.33E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9376(9-({[3-(trifluoromethyl)phenyl]methyl}amino)-1,2,3...)
Affinity DataIC50: 1.42E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9379((2E)-but-2-enedioic acid; 9-[(thiophen-2-ylmethyl)...)
Affinity DataIC50: 1.53E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9368(9-{[(4-fluorophenyl)methyl]amino}-1,2,3,4-tetrahyd...)
Affinity DataIC50: 1.67E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9377(9-({[4-(trifluoromethyl)phenyl]methyl}amino)-1,2,3...)
Affinity DataIC50: 1.81E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9383(6-fluoro-9-({[2-(trifluoromethyl)phenyl]methyl}ami...)
Affinity DataIC50: 2.01E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9374(9-{[(4-methylphenyl)methyl]amino}-1,2,3,4-tetrahyd...)
Affinity DataIC50: 2.10E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9370(9-{[(3-methoxyphenyl)methyl]amino}-1,2,3,4-tetrahy...)
Affinity DataIC50: 2.11E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9373(9-{[(3-methylphenyl)methyl]amino}-1,2,3,4-tetrahyd...)
Affinity DataIC50: 2.45E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9348((2Z)-but-2-enedioic acid; 9-amino-7-chloro-1,2,3,4...)
Affinity DataIC50: 2.47E+4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9365(9-{[(4-chlorophenyl)methyl]amino}-1,2,3,4-tetrahyd...)
Affinity DataIC50: 2.72E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9362((2Z)-but-2-enedioic acid; 9-(benzylamino)-1,2,3,4-...)
Affinity DataIC50: 3.22E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9369(9-{[(2-methoxyphenyl)methyl]amino}-1,2,3,4-tetrahy...)
Affinity DataIC50: 3.60E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9366((2Z)-but-2-enedioic acid; 9-{[(2-fluorophenyl)meth...)
Affinity DataIC50: 4.13E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9359(9-[(4,4-diphenylbutyl)amino]-1,2,3,4-tetrahydroacr...)
Affinity DataIC50: 4.93E+4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9361((2E)-but-2-enedioic acid; 9-{[4,4-bis(3-fluorophen...)
Affinity DataIC50: 6.30E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9384(9-(benzylamino)-6-(trifluoromethyl)-1,2,3,4-tetrah...)
Affinity DataIC50: 6.82E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

LigandPNGBDBM9360(9-{[4,4-bis(4-fluorophenyl)butyl]amino}-1,2,3,4-te...)
Affinity DataIC50: 8.78E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2006
Entry Details Article
PubMed