Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50048065
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50131550((S)-4-((S)-1-amino-3-(4-(difluoro(phosphono)methyl...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50308854([7-(4-{1-Benzotriazol-1-yl-2-[4-(difluoro-phosphon...)
Affinity DataIC50: 5nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50086955(4-[4'-(2-Benzyl-benzo[b]thiophen-3-yl)-3,5-dibromo...)
Affinity DataIC50: 30nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50308846(N-{(S)-1-(1H-Benzoimidazol-2-yl)-2-[3-methyl-4-(1,...)
Affinity DataIC50: 32nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50201800(CHEMBL3901092)
Affinity DataIC50: 270nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50209683((R)-2-(4-(9-bromo-2,3-dimethylnaphtho[2,3-b]thioph...)
Affinity DataIC50: 384nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50201806(CHEMBL3905288)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50308851(2-{4-[2-ACETYLAMINO-3-(4-CARBOXYMETHOXY-3-HYDROXY-...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50341986(6-hydroxy-3-(1-(2-(4-morpholinophenylamino)-2-oxoe...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)
Affinity DataIC50: 9.10E+5nMAssay Description:Inhibition of human recombinant GST-tagged CDC25B assessed as reduction in dephosphorylation of florigenic phosphatase substrate preincubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50201805(CHEMBL3903987)
Affinity DataIC50: 1.66E+6nMAssay Description:Inhibition of human recombinant GST-tagged CDC25B assessed as reduction in dephosphorylation of florigenic phosphatase substrate preincubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50346601(Oleanolic acid (OA)(Compound 1) | NSC-114945 | OLE...)
Affinity DataIC50: 2.39E+6nMAssay Description:Inhibition of human recombinant GST-tagged PTP1B catalytic domain expressed in Escherichia coli BL21-Conden plus (DE3) using pNPP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50201807(CHEMBL3934071)
Affinity DataIC50: 2.47E+6nMAssay Description:Inhibition of human recombinant GST-tagged CDC25B assessed as reduction in dephosphorylation of florigenic phosphatase substrate preincubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50201802(CHEMBL3981128)
Affinity DataIC50: 2.74E+6nMAssay Description:Inhibition of human recombinant GST-tagged CDC25B assessed as reduction in dephosphorylation of florigenic phosphatase substrate preincubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50201801(CHEMBL3942806)
Affinity DataIC50: 2.87E+6nMAssay Description:Inhibition of human recombinant GST-tagged CDC25B assessed as reduction in dephosphorylation of florigenic phosphatase substrate preincubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50201798(CHEMBL3944187)
Affinity DataIC50: 3.39E+6nMAssay Description:Inhibition of human recombinant GST-tagged CDC25B assessed as reduction in dephosphorylation of florigenic phosphatase substrate preincubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50201804(CHEMBL3952328)
Affinity DataIC50: 3.66E+6nMAssay Description:Inhibition of human recombinant GST-tagged CDC25B assessed as reduction in dephosphorylation of florigenic phosphatase substrate preincubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50201803(CHEMBL3908947)
Affinity DataIC50: 5.83E+6nMAssay Description:Inhibition of human recombinant GST-tagged CDC25B assessed as reduction in dephosphorylation of florigenic phosphatase substrate preincubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50201801(CHEMBL3942806)
Affinity DataIC50: 6.09E+6nMAssay Description:Inhibition of human recombinant GST-tagged PTP1B catalytic domain expressed in Escherichia coli BL21-Conden plus (DE3) using pNPP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50201798(CHEMBL3944187)
Affinity DataIC50: 6.83E+6nMAssay Description:Inhibition of human recombinant GST-tagged PTP1B catalytic domain expressed in Escherichia coli BL21-Conden plus (DE3) using pNPP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50201805(CHEMBL3903987)
Affinity DataIC50: 8.66E+6nMAssay Description:Inhibition of human recombinant GST-tagged PTP1B catalytic domain expressed in Escherichia coli BL21-Conden plus (DE3) using pNPP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2018
Entry Details Article
PubMed