Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50010035
TargetLysine-specific demethylase 5A(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534523(CHEMBL4560583)
Affinity DataIC50: 25nMAssay Description:Inhibition of full length human KDM5A using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate after 30 to 40 mins using 1 uM of 2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534529(CHEMBL4441819)
Affinity DataIC50: 50nMAssay Description:Inhibition of full length human KDM5A using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate after 30 to 40 mins using 1 uM of 2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 5B(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534523(CHEMBL4560583)
Affinity DataIC50: 70nMAssay Description:Inhibition of full length human KDM5B using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate after 30 to 40 mins using 2 uM of 2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534533(CHEMBL4471064)
Affinity DataIC50: 70nMAssay Description:Inhibition of full length human KDM5A using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate after 30 to 40 mins using 1 uM of 2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534525(CHEMBL4445747)
Affinity DataIC50: 160nMAssay Description:Inhibition of full length human KDM5A using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate after 30 to 40 mins using 1 uM of 2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534523(CHEMBL4560583)
Affinity DataIC50: 170nMAssay Description:Inhibition of full length human KDM5C using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate after 30 to 40 mins using 1 uM of 2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534534(CHEMBL4465724)
Affinity DataIC50: 230nMAssay Description:Inhibition of full length human KDM5A using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate after 30 to 40 mins using 1 uM of 2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534528(CHEMBL4520567)
Affinity DataIC50: 400nMAssay Description:Inhibition of full length human KDM5A using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate after 30 to 40 mins using 1 uM of 2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534535(CHEMBL4578848)
Affinity DataIC50: 700nMAssay Description:Inhibition of full length human KDM5A using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate after 30 to 40 mins using 1 uM of 2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534525(CHEMBL4445747)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of full length human KDM4C using biotinylated H2N-ARTKQTAR(KMe3)STGGKAPRKQLA-NTPEGBiot as substrate after 30 mins using 3 uM of 2-OG as co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534534(CHEMBL4465724)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of full length human KDM5A using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate after 30 to 40 mins using 20 uM of 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534522(CHEMBL4438400)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of full length human KDM5A using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate after 30 to 40 mins using 1 uM of 2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534526(CHEMBL4465314)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of full length human KDM5A using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate after 30 to 40 mins using 1 uM of 2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534532(CHEMBL4551596)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of full length human KDM5A using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate after 30 to 40 mins using 1 uM of 2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 2B(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534525(CHEMBL4445747)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of full length human KDM2B using biotinylated H2N-RKSAPATGGV(KMe2)KPHRYRPGTV-NTPEGBiot as substrate after 2 hrs using 0.3 uM of 2-OG as co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534523(CHEMBL4560583)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of full length human KDM4C using biotinylated H2N-ARTKQTAR(KMe3)STGGKAPRKQLA-NTPEGBiot as substrate after 30 mins using 3 uM of 2-OG as co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534531(CHEMBL326853)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of full length human KDM5A using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate after 30 to 40 mins using 1 uM of 2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534536(CHEMBL4443073)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of full length human KDM5A using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate after 30 to 40 mins using 1 uM of 2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534530(CHEMBL1975609)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of full length human KDM5A using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate after 30 to 40 mins using 1 uM of 2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534527(CHEMBL4569318)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of full length human KDM5A using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate after 30 to 40 mins using 1 uM of 2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534524(CHEMBL4522452)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of full length human KDM5A using biotinylated H2NART(KMe3)QTARKSTGGKAPRKQLA-NTPEG-biotin as substrate after 30 to 40 mins using 1 uM of 2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 2B(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50534523(CHEMBL4560583)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of full length human KDM2B using biotinylated H2N-RKSAPATGGV(KMe2)KPHRYRPGTV-NTPEGBiot as substrate after 2 hrs using 0.3 uM of 2-OG as co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed