Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50009842
TargetCytochrome P450 3A4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProthrombin(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human alpha-thrombin using S-2366 as substrate after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProthrombin(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human alpha-thrombin using S-2366 as substrate after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProthrombin(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi:  4.60nMAssay Description:Inhibition of human alpha-thrombin using S-2366 as substrate after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProthrombin(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi:  4.60nMAssay Description:Inhibition of human alpha-thrombin using S-2366 as substrate after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProthrombin(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532740(CHEMBL4518749)
Affinity DataKi:  200nMAssay Description:Inhibition of human alpha-thrombin using S-2366 as substrate after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProthrombin(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532740(CHEMBL4518749)
Affinity DataKi:  200nMAssay Description:Inhibition of human alpha-thrombin using S-2366 as substrate after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532740(CHEMBL4518749)
Affinity DataKi: >5.40E+3nMAssay Description:Inhibition of human trypsin 1 using S-2222 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi: >5.40E+3nMAssay Description:Inhibition of human trypsin 1 using S-2222 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi: >5.40E+3nMAssay Description:Inhibition of human trypsin 1 using S-2222 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532740(CHEMBL4518749)
Affinity DataKi: >5.40E+3nMAssay Description:Inhibition of human trypsin 1 using S-2222 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi: >5.40E+3nMAssay Description:Inhibition of human trypsin 1 using S-2222 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi: >5.40E+3nMAssay Description:Inhibition of human trypsin 1 using S-2222 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi: >1.70E+4nMAssay Description:Inhibition of human F10a using S-2765 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi: >1.70E+4nMAssay Description:Inhibition of human F10a using S-2765 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi: >1.70E+4nMAssay Description:Inhibition of human F10a using S-2765 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi: >1.70E+4nMAssay Description:Inhibition of human F10a using S-2765 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi: >1.90E+4nMAssay Description:Inhibition of human plasmin using S-2366 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi: >1.90E+4nMAssay Description:Inhibition of human plasmin using S-2366 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi: >1.90E+4nMAssay Description:Inhibition of human F11a using S-2366 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi: >1.90E+4nMAssay Description:Inhibition of human F11a using S-2366 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi: >1.90E+4nMAssay Description:Inhibition of human plasmin using S-2366 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi: >1.90E+4nMAssay Description:Inhibition of human F11a using S-2366 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi: >1.90E+4nMAssay Description:Inhibition of human plasmin using S-2366 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi: >1.90E+4nMAssay Description:Inhibition of human F11a using S-2366 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi: >2.90E+4nMAssay Description:Inhibition of human F9a using pefachrome F9a as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi: >2.90E+4nMAssay Description:Inhibition of human F9a using pefachrome F9a as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi: >2.90E+4nMAssay Description:Inhibition of human F9a using pefachrome F9a as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi: >2.90E+4nMAssay Description:Inhibition of human F9a using pefachrome F9a as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed