Compile Data Set for Download or QSAR
Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 50047657
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181512(CHEMBL3819277 | US10023539, Example WO 2006/07235...)
Affinity DataKd:  540nMAssay Description:Binding affinity to SMYD2 (unknown origin) by isothermal colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181506(CHEMBL3819038)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at PAR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50075102(CHEMBL3414623)
Affinity DataIC50: 15nMAssay Description:Inhibition of SMYD2 (unknown origin) expressed in Escherichia coli BL21 (DE3) using Biotinaminohexanoyl-GSRAHSSHLKSKKGQSTSRH as substrate after 75 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50180967(CHEMBL3818487)
Affinity DataIC50: 19nMAssay Description:Inhibition of SMYD2 (unknown origin) using H4 as substrate after 2hrs in presence 3H-SAM of by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50180955(CHEMBL3818617)
Affinity DataIC50: 27nMAssay Description:Inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using Btn-Ahx GSRAHSSHLKSKKGQSTSRH-amide as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181504(CHEMBL3818898)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at PAR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181502(CHEMBL3818510)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at PAR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50180973(CHEMBL3819284)
Affinity DataIC50: 38nMAssay Description:Inhibition of SMYD2 (unknown origin) using H4 as substrate after 2hrs in presence 3H-SAM of by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181505(CHEMBL3819204)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at PAR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50180968(CHEMBL3818080)
Affinity DataIC50: 44nMAssay Description:Inhibition of SMYD2 (unknown origin) using H4 as substrate after 2hrs in presence 3H-SAM of by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181507(CHEMBL3818421)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at PAR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50180971(CHEMBL3818322)
Affinity DataIC50: 50nMAssay Description:Inhibition of SMYD2 (unknown origin) using H4 as substrate after 2hrs in presence 3H-SAM of by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181513(CHEMBL3819237)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at PAR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50180955(CHEMBL3818617)
Affinity DataIC50: 60nMAssay Description:Inhibition of N-terminal 2xc-myc-tagged human SMYD2 transfected in human MDA-MB-231 cells assessed as reduction in AHNAK methylation after 72 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181511(CHEMBL3819343)
Affinity DataIC50: 60nMAssay Description:Antagonist activity at PAR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181509(CHEMBL3817930)
Affinity DataIC50: 60nMAssay Description:Antagonist activity at PAR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181512(CHEMBL3819277 | US10023539, Example WO 2006/07235...)
Affinity DataIC50: 70nMAssay Description:Antagonist activity at PAR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50180970(CHEMBL3819554)
Affinity DataIC50: 71nMAssay Description:Inhibition of SMYD2 (unknown origin) using H4 as substrate after 2hrs in presence 3H-SAM of by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181508(CHEMBL3818083 | US10023539, Example 4.2)
Affinity DataIC50: 80nMAssay Description:Inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using Btn-Ahx GSRAHSSHLKSKKGQSTSRH-amide as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50180974(CHEMBL3818092 | US10023539, Example 33.2)
Affinity DataIC50: 80nMAssay Description:Inhibition of SMYD2 (unknown origin) using H4 as substrate after 2hrs in presence 3H-SAM of by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181510(CHEMBL3818750)
Affinity DataIC50: 80nMAssay Description:Antagonist activity at PAR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50180978(CHEMBL3819515)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at PAR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50180969(CHEMBL3818526)
Affinity DataIC50: 119nMAssay Description:Inhibition of SMYD2 (unknown origin) using H4 as substrate after 2hrs in presence 3H-SAM of by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50396022(CHEMBL2169920)
Affinity DataIC50: 120nMAssay Description:Inhibition of SMYD2 (unknown origin) expressed in Escherichia coli BL21 (DE3) using Biotinaminohexanoyl-GSRAHSSHLKSKKGQSTSRH as substrate after 75 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50396022(CHEMBL2169920)
Affinity DataIC50: 120nMAssay Description:Inhibition of SMYD2 (unknown origin) expressed in Escherichia coli BL21 (DE3) using Biotinaminohexanoyl-GSRAHSSHLKSKKGQSTSRH as substrate after 75 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProteinase-activated receptor 1(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181454(CHEMBL3818932)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at PAR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50075102(CHEMBL3414623)
Affinity DataIC50: 388nMAssay Description:Inhibition of SMYD2 (unknown origin) using H4 as substrate after 2hrs in presence 3H-SAM of by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50180975(CHEMBL3818176)
Affinity DataIC50: 570nMAssay Description:Inhibition of SMYD2 (unknown origin) using H4 as substrate after 2hrs in presence 3H-SAM of by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50075102(CHEMBL3414623)
Affinity DataIC50: 600nMAssay Description:Inhibition of SMYD2 (unknown origin) expressed in human U2OS cells assessed as reduction in p53 methylation by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181512(CHEMBL3819277 | US10023539, Example WO 2006/07235...)
Affinity DataIC50: 800nMAssay Description:Inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using Btn-Ahx GSRAHSSHLKSKKGQSTSRH-amide as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50075102(CHEMBL3414623)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of SMYD2 (unknown origin) using H4 as substrate after 2hrs in presence 3H-SAM of by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50180976(CHEMBL3819310)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of SMYD2 (unknown origin) using H4 as substrate after 2hrs in presence 3H-SAM of by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50180955(CHEMBL3818617)
Affinity DataIC50: 1.70E+3nMAssay Description:Antagonist activity at PAR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181501(CHEMBL3818589)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using Btn-Ahx GSRAHSSHLKSKKGQSTSRH-amide as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181509(CHEMBL3817930)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using Btn-Ahx GSRAHSSHLKSKKGQSTSRH-amide as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181503(CHEMBL3819513)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using Btn-Ahx GSRAHSSHLKSKKGQSTSRH-amide as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181510(CHEMBL3818750)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using Btn-Ahx GSRAHSSHLKSKKGQSTSRH-amide as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181454(CHEMBL3818932)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using Btn-Ahx GSRAHSSHLKSKKGQSTSRH-amide as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50396022(CHEMBL2169920)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of N-terminal 2xc-myc-tagged human SMYD2 transfected in human MDA-MB-231 cells assessed as reduction in AHNAK methylation after 72 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181513(CHEMBL3819237)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using Btn-Ahx GSRAHSSHLKSKKGQSTSRH-amide as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50180972(CHEMBL3817978)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of SMYD2 (unknown origin) using H4 as substrate after 2hrs in presence 3H-SAM of by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50180978(CHEMBL3819515)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of SMYD2 (unknown origin) using H4 as substrate after 2hrs in presence 3H-SAM of by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181507(CHEMBL3818421)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using Btn-Ahx GSRAHSSHLKSKKGQSTSRH-amide as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181505(CHEMBL3819204)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using Btn-Ahx GSRAHSSHLKSKKGQSTSRH-amide as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50396022(CHEMBL2169920)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SMYD2 (unknown origin) expressed in human U2OS cells assessed as reduction in p53 methylation by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181500(CHEMBL3817959)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using Btn-Ahx GSRAHSSHLKSKKGQSTSRH-amide as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181511(CHEMBL3819343)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using Btn-Ahx GSRAHSSHLKSKKGQSTSRH-amide as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50180977(CHEMBL3817947)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of SMYD2 (unknown origin) using H4 as substrate after 2hrs in presence 3H-SAM of by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181504(CHEMBL3818898)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using Btn-Ahx GSRAHSSHLKSKKGQSTSRH-amide as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50181506(CHEMBL3819038)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using Btn-Ahx GSRAHSSHLKSKKGQSTSRH-amide as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
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