Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50010181
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50535803(CHEMBL4554678)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of GST-tagged human PTP1B expressed in Escherichia coli using pNPP substrate assessed as reduction in p-nitrophenol releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50535802(CHEMBL4567748)
Affinity DataIC50: 3.44E+3nMAssay Description:Inhibition of recombinant human PTP1B preincubated for 10 mins followed by protein addition using pNPP substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50374279(OHIOENSIN A)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of GST-tagged human PTP1B expressed in Escherichia coli using pNPP substrate assessed as reduction in p-nitrophenol releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50374277(CHEMBL403094)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of GST-tagged human PTP1B expressed in Escherichia coli using pNPP substrate assessed as reduction in p-nitrophenol releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50374280(CHEMBL403411)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of GST-tagged human PTP1B expressed in Escherichia coli using pNPP substrate assessed as reduction in p-nitrophenol releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50535808(CHEMBL4524583)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of GST-tagged human PTP1B expressed in Escherichia coli using pNPP substrate assessed as reduction in p-nitrophenol releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50093526(CHEMBL426373 | RK-682)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of recombinant human PTP1B preincubated for 10 mins followed by protein addition using pNPP substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50535804(CHEMBL4561426)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of GST-tagged human PTP1B expressed in Escherichia coli using pNPP substrate assessed as reduction in p-nitrophenol releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50535805(CHEMBL4566713)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of GST-tagged human PTP1B expressed in Escherichia coli using pNPP substrate assessed as reduction in p-nitrophenol releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50535800(CHEMBL4541029)
Affinity DataIC50: 6.27E+3nMAssay Description:Inhibition of recombinant human PTP1B preincubated for 10 mins followed by protein addition using pNPP substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50391058(CHEMBL2086414)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of GST-tagged human PTP1B expressed in Escherichia coli using pNPP substrate assessed as reduction in p-nitrophenol releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250341(23-hydroxyursolic acid | CHEMBL523622)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of GST-tagged human PTP1B expressed in Escherichia coli using pNPP substrate assessed as reduction in p-nitrophenol releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50535801(CHEMBL4528277)
Affinity DataIC50: 7.67E+3nMAssay Description:Inhibition of recombinant human PTP1B preincubated for 10 mins followed by protein addition using pNPP substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50535807(CHEBI:69561 | Lobophytumin C)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of GST-tagged human PTP1B expressed in Escherichia coli using pNPP substrate assessed as reduction in p-nitrophenol releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50535806(CHEMBL4535279)
Affinity DataIC50: 1.26E+6nMAssay Description:Inhibition of recombinant human PTP1B preincubated for 10 mins followed by protein addition using pNPP substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed