Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50047391
TargetWD repeat-containing protein 5(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50164788(CHEMBL3800271)
Affinity DataKd:  390nMAssay Description:Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50164796(CHEMBL3800054)
Affinity DataKd:  50nMAssay Description:Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50164795(CHEMBL3799608)
Affinity DataKd:  30nMAssay Description:Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50164794(CHEMBL3798846 | US11174250, Example Table4.1.1 | U...)
Affinity DataKd:  30nMAssay Description:Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50164793(CHEMBL3799840)
Affinity DataKd:  50nMAssay Description:Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50164770(CHEMBL3799275)
Affinity DataKd:  50nMAssay Description:Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50164792(CHEMBL3798198)
Affinity DataKd:  40nMAssay Description:Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50164791(CHEMBL3799704)
Affinity DataKd:  40nMAssay Description:Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50164790(CHEMBL3797611)
Affinity DataKd:  340nMAssay Description:Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50164789(CHEMBL3798578)
Affinity DataKd:  330nMAssay Description:Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50164786(CHEMBL3798573)
Affinity DataKd:  720nMAssay Description:Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50428271(CHEMBL2337032)
Affinity DataKd:  380nMAssay Description:Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetWD repeat-containing protein 5(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50164785(CHEMBL3797967)
Affinity DataKd:  210nMAssay Description:Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50164773(CHEMBL3799127)
Affinity DataKd:  40nMAssay Description:Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50164787(CHEMBL3798088)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of SUMO-His-tagged WDR5 (unknown origin) interaction with MLL1 assessed as displacement of fluorescence labelled Ac-ARA peptide substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM200712(US9233086, 10A)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of N-terminal His-tagged WDR5 (24 to 334 residues) (unknown origin) interaction with MLL1 assessed as displacement of 5-Lys-FAM peptide su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase 2A(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50164787(CHEMBL3798088)
Affinity DataIC50: 320nMAssay Description:Inhibition of SUMO-His-tagged MLL1 activity (unknown origin) expressed in Escherichia coli BL21(DE3) pLysS cells using histone H3 as substrate by sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50164770(CHEMBL3799275)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant FLT3 expressed in insect cells using Ulight-CAGAGAIETDKEYYTVKD as substrate after 90 mins by LANCE assay in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50164770(CHEMBL3799275)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant FLT4 using Ulight-CAGAGAIETDKEYYTVKD as substrate after 90 mins by LANCE assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed