Compile Data Set for Download or QSAR
Report error Found 59 Enz. Inhib. hit(s) with all data for entry = 50047288
TargetEphrin type-B receptor 4(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157880(CHEMBL3787112)
Affinity DataIC50: 5nMAssay Description:Inhibition of EphB4 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157880(CHEMBL3787112)
Affinity DataIC50: 8nMAssay Description:Inhibition of Ret (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157878(CHEMBL3786567)
Affinity DataIC50: 9nMAssay Description:Inhibition of IGF-1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157888(CHEMBL3785273)
Affinity DataIC50: 60nMAssay Description:Inhibition of IGF-1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157879(CHEMBL1614712)
Affinity DataIC50: 61nMAssay Description:Inhibition of IGF-1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157894(CHEMBL3786383)
Affinity DataIC50: 80nMAssay Description:Inhibition of IGF-1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157881(CHEMBL3787614)
Affinity DataIC50: 80nMAssay Description:Inhibition of IGF-1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157878(CHEMBL3786567)
Affinity DataIC50: 100nMAssay Description:Inhibition of Ins receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157887(CHEMBL3786793)
Affinity DataIC50: 110nMAssay Description:Inhibition of IGF-1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157895(CHEMBL3787668)
Affinity DataIC50: 130nMAssay Description:Inhibition of IGF-1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157879(CHEMBL1614712)
Affinity DataIC50: 130nMAssay Description:Inhibition of human ERG by dofetilide binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157900(CHEMBL3786598)
Affinity DataIC50: 160nMAssay Description:Inhibition of IGF-1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157880(CHEMBL3787112)
Affinity DataIC50: 230nMAssay Description:Inhibition of PI3K-beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157899(CHEMBL3786472)
Affinity DataIC50: 260nMAssay Description:Inhibition of IGF-1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157880(CHEMBL3787112)
Affinity DataIC50: 260nMAssay Description:Inhibition of Jak1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157898(CHEMBL3785927)
Affinity DataIC50: 310nMAssay Description:Inhibition of IGF-1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157883(CHEMBL3786115)
Affinity DataIC50: 370nMAssay Description:Inhibition of IGF-1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157880(CHEMBL3787112)
Affinity DataIC50: 420nMAssay Description:Inhibition of IGF-1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157880(CHEMBL3787112)
Affinity DataIC50: 420nMAssay Description:Inhibition of human ERG by dofetilide binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157880(CHEMBL3787112)
Affinity DataIC50: 440nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157882(CHEMBL3785169)
Affinity DataIC50: 490nMAssay Description:Inhibition of IGF-1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157892(CHEMBL3787399)
Affinity DataIC50: 550nMAssay Description:Inhibition of IGF-1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157897(CHEMBL3786668)
Affinity DataIC50: 630nMAssay Description:Inhibition of IGF-1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157880(CHEMBL3787112)
Affinity DataIC50: 690nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157878(CHEMBL3786567)
Affinity DataIC50: 690nMAssay Description:Inhibition of EphB4 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157886(CHEMBL3786564)
Affinity DataIC50: 840nMAssay Description:Inhibition of IGF-1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157881(CHEMBL3787614)
Affinity DataIC50: 930nMAssay Description:Inhibition of Ins receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157878(CHEMBL3786567)
Affinity DataIC50: 970nMAssay Description:Inhibition of Ret (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157879(CHEMBL1614712)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Ins receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157880(CHEMBL3787112)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of PI3K-alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157885(CHEMBL3787253)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of IGF-1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157893(CHEMBL3787579)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of IGF-1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157880(CHEMBL3787112)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Her1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157881(CHEMBL3787614)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of EphB4 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157879(CHEMBL1614712)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of Ret (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157881(CHEMBL3787614)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human ERG by dofetilide binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157891(CHEMBL3785519)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of IGF-1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157880(CHEMBL3787112)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of Ins receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157881(CHEMBL3787614)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of Ret (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157879(CHEMBL1614712)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157881(CHEMBL3787614)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157879(CHEMBL1614712)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157878(CHEMBL3786567)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157896(CHEMBL3787474)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of IGF-1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157881(CHEMBL3787614)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157879(CHEMBL1614712)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of PI3K-beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157881(CHEMBL3787614)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of PI3K-beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157878(CHEMBL3786567)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of PI3K-beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157879(CHEMBL1614712)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of PI3K-alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50157881(CHEMBL3787614)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of PI3K-alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
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