Compile Data Set for Download or QSAR
Report error Found 69 Enz. Inhib. hit(s) with all data for entry = 50047081
TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148158(CHEMBL3764017)
Affinity DataEC50:  3.00E+3nMAssay Description:Transactivation of human PXR expressed in human HepG2 cells after 15 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148158(CHEMBL3764017)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148192(CHEMBL3765578)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant DAGLalpha expressed in African green monkey COS cells using sn-1-stearoyl-2-[14C]-arachidonoyl-glycerol as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148184(CHEMBL3763853)
Affinity DataIC50: 3nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148193(CHEMBL3765716)
Affinity DataIC50: 3nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148188(CHEMBL3763826)
Affinity DataIC50: 3nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148154(CHEMBL3763831)
Affinity DataIC50: 4nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148187(CHEMBL3764093)
Affinity DataIC50: 6nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50147618(CHEMBL3765022)
Affinity DataIC50: 8nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148191(CHEMBL3763430)
Affinity DataIC50: 8nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50147612(CHEMBL3765158)
Affinity DataIC50: 11nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148184(CHEMBL3763853)
Affinity DataIC50: 14nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cells using DAG as substrate assessed as reduction in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50147615(CHEMBL3764876)
Affinity DataIC50: 14nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cells using DAG as substrate assessed as reduction in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50147615(CHEMBL3764876)
Affinity DataIC50: 14.3nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cells using DAG as substrate assessed as reduction in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148157(CHEMBL3765824)
Affinity DataIC50: 16nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50147613(CHEMBL3764778)
Affinity DataIC50: 17nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148183(CHEMBL3764377)
Affinity DataIC50: 17nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148155(CHEMBL3765573)
Affinity DataIC50: 18nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50048620(CHEMBL3319620)
Affinity DataIC50: 18nMAssay Description:Inhibition of DAGLalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 20nMAssay Description:Inhibition of DAGLalpha in mouse N18TG2 cells assessed as inhibition of ionomycin-induced formation of 2-AG incubated for 20 mins by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148161(CHEMBL3765546)
Affinity DataIC50: 30nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148158(CHEMBL3764017)
Affinity DataIC50: 37nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cells using DAG as substrate assessed as reduction in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-beta(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148158(CHEMBL3764017)
Affinity DataIC50: 40nMAssay Description:Inhibition of DAGLbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-beta(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50147615(CHEMBL3764876)
Affinity DataIC50: 40nMAssay Description:Inhibition of DAGLbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50147614(CHEMBL3764349)
Affinity DataIC50: 40nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148153(CHEMBL3765562)
Affinity DataIC50: 45nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148189(CHEMBL3764044)
Affinity DataIC50: 55nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148183(CHEMBL3764377)
Affinity DataIC50: 60nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cells using DAG as substrate assessed as reduction in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148156(CHEMBL3763964)
Affinity DataIC50: 60nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148190(CHEMBL3765750)
Affinity DataIC50: 80nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148181(CHEMBL3765634)
Affinity DataIC50: 80nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-beta(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148187(CHEMBL3764093)
Affinity DataIC50: 80nMAssay Description:Inhibition of DAGLbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50147618(CHEMBL3765022)
Affinity DataIC50: 82nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cells using DAG as substrate assessed as reduction in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50147617(CHEMBL3765421)
Affinity DataIC50: 88nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cells using DAG as substrate assessed as reduction in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50147617(CHEMBL3765421)
Affinity DataIC50: 88nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cells using DAG as substrate assessed as reduction in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50147616(CHEMBL3765497)
Affinity DataIC50: 100nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cells using DAG as substrate assessed as reduction in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50147616(CHEMBL3765497)
Affinity DataIC50: 100nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cells using DAG as substrate assessed as reduction in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-beta(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50147618(CHEMBL3765022)
Affinity DataIC50: 112nMAssay Description:Inhibition of DAGLbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148152(CHEMBL3764007)
Affinity DataIC50: 130nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-beta(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50147617(CHEMBL3765421)
Affinity DataIC50: 146nMAssay Description:Inhibition of DAGLbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148151(CHEMBL3764430)
Affinity DataIC50: 161nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-beta(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 420nMAssay Description:Inhibition of DAGLbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148160(CHEMBL3763708)
Affinity DataIC50: 510nMAssay Description:Inhibition of full length human C-terminal HA-tagged DAGLalpha expressed in HEK293 cell membrane using DAG as substrate incubated for 20 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148158(CHEMBL3764017)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate incubated for 10 mins by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50147618(CHEMBL3765022)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 7 mins by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50147618(CHEMBL3765022)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 5 mins by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148158(CHEMBL3764017)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 5 mins by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148158(CHEMBL3764017)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using (S)-mephenytoin as substrate incubated for 5 mins by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50148183(CHEMBL3764377)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
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