Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50047174
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Md Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152144BDBM50152144(CHEMBL3781661)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Md Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152127BDBM50152127(CHEMBL3780962)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Md Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152129BDBM50152129(CHEMBL3780596)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Md Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152130BDBM50152130(CHEMBL3780613)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Md Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152145BDBM50152145(CHEMBL3780032)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Md Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152125BDBM50152125(CHEMBL3781316)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant human MTH1 assessed as hydrolysis of dGTP to dGMP and pyrophosphate after 15 mins by malachite green-based microplate reade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Md Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152125BDBM50152125(CHEMBL3781316)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Md Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152126BDBM50152126(CHEMBL3780321)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Md Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152131BDBM50152131(CHEMBL3781917)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Md Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152138BDBM50152138(CHEMBL3781015)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Md Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152124BDBM50152124(CHEMBL3782004)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human MTH1 assessed as hydrolysis of dGTP to dGMP and pyrophosphate after 15 mins by malachite green-based microplate reade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Md Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152139BDBM50152139(CHEMBL3780307)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Md Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152124BDBM50152124(CHEMBL3782004)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Md Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152140BDBM50152140(CHEMBL3781296)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Md Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152143BDBM50152143(CHEMBL3781387)
Affinity DataIC50: 53nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Md Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152132BDBM50152132(CHEMBL3781861)
Affinity DataIC50: 84nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Md Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152142BDBM50152142(CHEMBL3781493)
Affinity DataIC50: 112nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Md Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152134BDBM50152134(CHEMBL3781662)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Md Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152141BDBM50152141(CHEMBL3780652)
Affinity DataIC50: 302nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Md Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152136BDBM50152136(CHEMBL3781282)
Affinity DataIC50: 332nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Md Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152122BDBM50152122(CHEMBL3780535)
Affinity DataIC50: 850nMAssay Description:Inhibition of MTH1 in human U2OS cells assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate after 1 hr by PPiLight assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Md Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152137BDBM50152137(CHEMBL3781267)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed