Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50011511
Affinity DataEC50: 10nMAssay Description:Binding affinity to MTH1 in human K562 cells assessed as thermal stabilization preincubated for 30 mins followed by heating at 52 degree C for 3 mins...More data for this Ligand-Target Pair
Affinity DataEC50: 3.60E+3nMAssay Description:Binding affinity to MTH1 in human K562 cells assessed as thermal stabilization preincubated for 30 mins followed by heating at 52 degree C for 3 mins...More data for this Ligand-Target Pair
Affinity DataEC50: 1.26E+3nMAssay Description:Agonist activity at TLR7 in human PBMC assessed as induction of IN-12 stimulationMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataEC50: 944nMAssay Description:Agonist activity at TLR7 in human PBMC assessed as induction of IN-12 stimulationMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TLR7 in human PBMC assessed as induction of IN-12 stimulationMore data for this Ligand-Target Pair
Affinity DataKd: 440nMAssay Description:Binding affinity to recombinant His-tagged MTH1 isoform p18 (M1 to V156 residues) (unknown origin) assessed as dissociation constant by surface plasm...More data for this Ligand-Target Pair
Affinity DataKd: 0.200nMAssay Description:Binding affinity to recombinant His-tagged MTH1 isoform p18 (M1 to V156 residues) (unknown origin) assessed as dissociation constant by surface plasm...More data for this Ligand-Target Pair
Affinity DataKd: 0.400nMAssay Description:Binding affinity to recombinant His-tagged MTH1 isoform p18 (M1 to V156 residues) (unknown origin) assessed as dissociation constant by surface plasm...More data for this Ligand-Target Pair
Affinity DataKd: 0.5nMAssay Description:Binding affinity to recombinant His-tagged MTH1 isoform p18 (M1 to V156 residues) (unknown origin) assessed as dissociation constant by surface plasm...More data for this Ligand-Target Pair
Affinity DataKd: 0.200nMAssay Description:Binding affinity to recombinant His-tagged MTH1 isoform p18 (M1 to V156 residues) (unknown origin) assessed as dissociation constant by surface plasm...More data for this Ligand-Target Pair
Affinity DataKd: 5nMAssay Description:Binding affinity to recombinant His-tagged MTH1 isoform p18 (M1 to V156 residues) (unknown origin) assessed as dissociation constant by surface plasm...More data for this Ligand-Target Pair
Affinity DataKd: 39nMAssay Description:Binding affinity to recombinant His-tagged MTH1 isoform p18 (M1 to V156 residues) (unknown origin) assessed as dissociation constant by surface plasm...More data for this Ligand-Target Pair
Affinity DataEC50: 1.50E+3nMAssay Description:Binding affinity to MTH1 in human K562 cells assessed as thermal stabilization preincubated for 30 mins followed by heating at 52 degree C for 3 mins...More data for this Ligand-Target Pair
Affinity DataEC50: 9nMAssay Description:Binding affinity to MTH1 in human K562 cells assessed as thermal stabilization preincubated for 30 mins followed by heating at 52 degree C for 3 mins...More data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Binding affinity to MTH1 in human K562 cells assessed as thermal stabilization preincubated for 30 mins followed by heating at 52 degree C for 3 mins...More data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Binding affinity to MTH1 in human K562 cells assessed as thermal stabilization preincubated for 30 mins followed by heating at 52 degree C for 3 mins...More data for this Ligand-Target Pair
Affinity DataEC50: 950nMAssay Description:Binding affinity to MTH1 in human K562 cells assessed as thermal stabilization preincubated for 30 mins followed by heating at 52 degree C for 3 mins...More data for this Ligand-Target Pair
Affinity DataEC50: 80nMAssay Description:Binding affinity to MTH1 in human K562 cells assessed as thermal stabilization preincubated for 30 mins followed by heating at 52 degree C for 3 mins...More data for this Ligand-Target Pair
Affinity DataKd: 3nMAssay Description:Binding affinity to recombinant His-tagged MTH1 isoform p18 (M1 to V156 residues) (unknown origin) assessed as dissociation constant by surface plasm...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 138nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 153nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 536nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 646nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 888nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.81E+3nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.32E+3nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.75E+3nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
