Compile Data Set for Download or QSAR
Report error Found 97 Enz. Inhib. hit(s) with all data for entry = 50018876
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613517(CHEMBL5273346)
Affinity DataKi:  0.0700nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613518(CHEMBL5289754)
Affinity DataKi:  0.130nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613552(CHEMBL5281808)
Affinity DataKi:  0.160nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613546(CHEMBL5273114)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613519(CHEMBL5281912)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613478(CHEMBL5273273)
Affinity DataKi:  0.280nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613548(CHEMBL5286081)
Affinity DataKi:  0.290nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613519(CHEMBL5281912)
Affinity DataEC50:  0.360nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells assessed as ERK phosphorylation incubated for 2 hrs by Alphascreen surefire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613528(CHEMBL5282326)
Affinity DataEC50:  0.390nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50002184(Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Ly...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613519(CHEMBL5281912)
Affinity DataEC50:  0.410nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613550(CHEMBL5279208)
Affinity DataKi:  0.420nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613528(CHEMBL5282326)
Affinity DataKi:  0.480nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613547(CHEMBL5278935)
Affinity DataKi:  0.590nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613551(CHEMBL5283035)
Affinity DataKi:  0.590nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613520(CHEMBL5283811)
Affinity DataKi:  0.590nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613545(CHEMBL5288658)
Affinity DataKi:  0.610nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613528(CHEMBL5282326)
Affinity DataEC50:  0.620nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells assessed as ERK phosphorylation incubated for 2 hrs by Alphascreen surefire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613513(CHEMBL5280997)
Affinity DataKi:  0.640nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613514(CHEMBL5284775)
Affinity DataKi:  0.710nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613515(CHEMBL5276702)
Affinity DataKi:  0.910nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613478(CHEMBL5273273)
Affinity DataEC50:  0.950nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells assessed as ERK phosphorylation incubated for 2 hrs by Alphascreen surefire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613521(CHEMBL5285730)
Affinity DataKi:  0.980nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613522(CHEMBL5270523)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613511(CHEMBL5278992)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613510(CHEMBL5282859)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613516(CHEMBL5275165)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613478(CHEMBL5273273)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613524(CHEMBL5289642)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613494(CHEMBL5280066)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613549(CHEMBL5283084)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613491(CHEMBL5283510)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613512(CHEMBL5276129)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613523(CHEMBL5279518)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613532(CHEMBL5288155)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613496(CHEMBL5266718)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613506(CHEMBL5268886)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613508(CHEMBL5288478)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613507(CHEMBL5280357)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613509(CHEMBL5271178)
Affinity DataKi:  6.70nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613503(CHEMBL5267287)
Affinity DataKi:  6.70nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613533(CHEMBL5276505)
Affinity DataKi:  7.80nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613553(CHEMBL5276565)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613524(CHEMBL5289642)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613486(CHEMBL5281790)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613506(CHEMBL5268886)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613504(CHEMBL5274492)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613503(CHEMBL5267287)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613526(CHEMBL5288247)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xenome

Curated by ChEMBL
LigandPNGBDBM50613505(CHEMBL5268235)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO-K1 cells incubated for 1 hr by 1450 microbeta scintillation counter anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
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