Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50047280
TargetHistone deacetylase 4(Human)
Biofocus

Curated by ChEMBL
LigandPNGBDBM50160879(US9505736, (1S,2S,3S)-1-Fluoro-2-(4-(5- fluoropyri...)
Affinity DataKd:  20nMAssay Description:Binding affinity to HDAC4 catalytic domain (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Biofocus

Curated by ChEMBL
LigandPNGBDBM50161830(CHEMBL3793439)
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC4 catalytic domain (unknown origin) using Boc-Lys(TFA)-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Biofocus

Curated by ChEMBL
LigandPNGBDBM50160874(US9505736, (1S,2S,3S)-2-(4-(5- (Difluoromethoxy)py...)
Affinity DataIC50: 30nMAssay Description:Inhibition of HDAC4 catalytic domain (unknown origin) using Boc-Lys(TFA)-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Biofocus

Curated by ChEMBL
LigandPNGBDBM50161829(CHEMBL3794140)
Affinity DataIC50: 40nMAssay Description:Inhibition of HDAC4 catalytic domain (unknown origin) using Boc-Lys(TFA)-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Biofocus

Curated by ChEMBL
LigandPNGBDBM50161831(US9505736, (1S,2S,3S)-1-Fluoro-N-hydroxy-2-phenyl-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of HDAC4 catalytic domain (unknown origin) using Boc-Lys(TFA)-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Biofocus

Curated by ChEMBL
LigandPNGBDBM50160875(CHEMBL3794334 | US9765054, Compound 50d)
Affinity DataIC50: 80nMAssay Description:Inhibition of HDAC4 catalytic domain (unknown origin) using Boc-Lys(TFA)-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Biofocus

Curated by ChEMBL
LigandPNGBDBM50160873(CHEMBL3794544 | US9765054, Compound 50j)
Affinity DataIC50: 140nMAssay Description:Inhibition of HDAC4 catalytic domain (unknown origin) using Boc-Lys(TFA)-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Biofocus

Curated by ChEMBL
LigandPNGBDBM50160874(US9505736, (1S,2S,3S)-2-(4-(5- (Difluoromethoxy)py...)
Affinity DataIC50: 150nMAssay Description:Inhibition of HDAC4 in human Jurkat E6-1 cells using Lys-TFA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Biofocus

Curated by ChEMBL
LigandPNGBDBM50161829(CHEMBL3794140)
Affinity DataIC50: 230nMAssay Description:Inhibition of HDAC4 in human Jurkat E6-1 cells using Lys-TFA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Biofocus

Curated by ChEMBL
LigandPNGBDBM50160873(CHEMBL3794544 | US9765054, Compound 50j)
Affinity DataIC50: 430nMAssay Description:Inhibition of HDAC4 in human Jurkat E6-1 cells using Lys-TFA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Biofocus

Curated by ChEMBL
LigandPNGBDBM50155843(CHEMBL3793034 | US9765054, Compound 50K)
Affinity DataIC50: 510nMAssay Description:Inhibition of HDAC4 in human Jurkat E6-1 cells using Lys-TFA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Biofocus

Curated by ChEMBL
LigandPNGBDBM50155804(CHEMBL3793569)
Affinity DataIC50: 730nMAssay Description:Inhibition of HDAC4 in human Jurkat E6-1 cells using Lys-TFA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Biofocus

Curated by ChEMBL
LigandPNGBDBM50155803(US9505736, (1S,2S,3S)-1-Chloro-N-hydroxy-2-(4-(5- ...)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of HDAC4 in human Jurkat E6-1 cells using Lys-TFA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed