Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50047245
TargetMitogen-activated protein kinase 14(Human)
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataKd:  27nMAssay Description:Binding affinity to P38-alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50237710(AMN 107 | AMN107 | 4-methyl-N-[3-(4-methyl-1H-imid...)
Affinity DataKd:  460nMAssay Description:Binding affinity to P38-alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataKd:  0.210nMAssay Description:Binding affinity to SRC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProto-oncogene tyrosine-protein kinase Src(Human)
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataKd:  1nMAssay Description:Binding affinity to SRC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50156123(CHEMBL3780219)
Affinity DataIC50: 62nMAssay Description:Inhibition of full length recombinant GST-tagged human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50156123(CHEMBL3780219)
Affinity DataIC50: 70nMAssay Description:Inhibition of full length recombinant human ABL1 expressed in Baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50156123(CHEMBL3780219)
Affinity DataIC50: 90nMAssay Description:Inhibition of full length recombinant human C-terminal His-tagged SRC expressed in Baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50156123(CHEMBL3780219)
Affinity DataIC50: 292nMAssay Description:Inhibition of GST-tagged human DDR1 (440 to 876 residues) expressed in Baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50156123(CHEMBL3780219)
Affinity DataIC50: 457nMAssay Description:Inhibition of recombinant human GST-tagged DDR2 expressed in Baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50156123(CHEMBL3780219)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of His-tagged recombinant human c-Kit without catalytic domain expressed in mammalian expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed