Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50047065
TargetProtein cereblon(Human)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50146598(CHEMBL3764647)
Affinity DataKd:  7.90E+3nMAssay Description:Binding affinity to human CRBN (delta 1 to 315) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2017
Entry Details Article
PubMed
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50146598(CHEMBL3764647)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to wild type Magnetospirillum gryphiswaldense cereblon isoform 4 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2017
Entry Details Article
PubMed
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM7814(pyrrolidine-2,5-dione | Maleimide-Related Compound...)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of MANT-uracil binding to wild type Magnetospirillum gryphiswaldense cereblon isoform 4 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2017
Entry Details Article
PubMed
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50070114(CHEMBL468 | 2-(2,6-dioxopiperidin-3-yl)isoindoline...)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of MANT-uracil binding to wild type Magnetospirillum gryphiswaldense cereblon isoform 4 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2017
Entry Details Article
PubMed
TargetProtein cereblon(Human)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50070114(CHEMBL468 | 2-(2,6-dioxopiperidin-3-yl)isoindoline...)
Affinity DataIC50: 2.99E+4nMAssay Description:Inhibition of MANT-uracil binding to human CRBN (delta 1 to 315) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2017
Entry Details Article
PubMed
TargetProtein cereblon(Human)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM7814(pyrrolidine-2,5-dione | Maleimide-Related Compound...)
Affinity DataIC50: 3.45E+4nMAssay Description:Inhibition of MANT-uracil binding to human CRBN (delta 1 to 315) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2017
Entry Details Article
PubMed
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50146597(CHEMBL3763941)
Affinity DataIC50: 4.89E+4nMAssay Description:Inhibition of MANT-uracil binding to wild type Magnetospirillum gryphiswaldense cereblon isoform 4 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProtein cereblon(Human)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50146597(CHEMBL3763941)
Affinity DataIC50: 1.36E+5nMAssay Description:Inhibition of MANT-uracil binding to human CRBN (delta 1 to 315) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2017
Entry Details Article
PubMed
TargetProtein cereblon(Human)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50026473(sulfonyldimethane | Sulfonylbismethane | dimethyl ...)
Affinity DataIC50: 1.81E+8nMAssay Description:Inhibition of MANT-uracil binding to human CRBN (delta 1 to 315) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2017
Entry Details Article
PubMed
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50026473(sulfonyldimethane | Sulfonylbismethane | dimethyl ...)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of MANT-uracil binding to wild type Magnetospirillum gryphiswaldense cereblon isoform 4 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2017
Entry Details Article
PubMed
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM7814(pyrrolidine-2,5-dione | Maleimide-Related Compound...)
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of MANT-uracil binding to wild type Magnetospirillum gryphiswaldense cereblon isoform 4 by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2017
Entry Details Article
PubMed
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50070114(CHEMBL468 | 2-(2,6-dioxopiperidin-3-yl)isoindoline...)
Affinity DataKi:  4.40E+3nMAssay Description:Inhibition of MANT-uracil binding to wild type Magnetospirillum gryphiswaldense cereblon isoform 4 by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2017
Entry Details Article
PubMed
TargetProtein cereblon(Human)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50070114(CHEMBL468 | 2-(2,6-dioxopiperidin-3-yl)isoindoline...)
Affinity DataKi:  2.27E+4nMAssay Description:Inhibition of MANT-uracil binding to human CRBN (delta 1 to 315) by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2017
Entry Details Article
PubMed
TargetProtein cereblon(Human)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM7814(pyrrolidine-2,5-dione | Maleimide-Related Compound...)
Affinity DataKi:  2.62E+4nMAssay Description:Inhibition of MANT-uracil binding to human CRBN (delta 1 to 315) by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2017
Entry Details Article
PubMed
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50146597(CHEMBL3763941)
Affinity DataKi:  2.78E+4nMAssay Description:Inhibition of MANT-uracil binding to wild type Magnetospirillum gryphiswaldense cereblon isoform 4 by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProtein cereblon(Human)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50146597(CHEMBL3763941)
Affinity DataKi:  1.03E+5nMAssay Description:Inhibition of MANT-uracil binding to human CRBN (delta 1 to 315) by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2017
Entry Details Article
PubMed
TargetProtein cereblon(Human)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50026473(sulfonyldimethane | Sulfonylbismethane | dimethyl ...)
Affinity DataKi:  1.37E+8nMAssay Description:Inhibition of MANT-uracil binding to human CRBN (delta 1 to 315) by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2017
Entry Details Article
PubMed
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50026473(sulfonyldimethane | Sulfonylbismethane | dimethyl ...)
Affinity DataKi:  5.69E+6nMAssay Description:Inhibition of MANT-uracil binding to wild type Magnetospirillum gryphiswaldense cereblon isoform 4 by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2017
Entry Details Article
PubMed