Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50047063
TargetSerine/threonine-protein kinase B-raf(Human)
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | VEMURAFENIB | US...)
Affinity DataIC50: 280nMAssay Description:Inhibition of B-Raf V600E mutant (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | VEMURAFENIB | US...)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of wild-type B-Raf (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM50146591(CHEMBL3763692)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of B-Raf V600E mutant (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM50146588(CHEMBL3764145)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of B-Raf V600E mutant (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM50146589(CHEMBL3765683)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of B-Raf V600E mutant (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM50146587(CHEMBL3764571)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of B-Raf V600E mutant (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM50146590(CHEMBL3765068)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of B-Raf V600E mutant (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM50146587(CHEMBL3764571)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of wild-type B-Raf (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM50146590(CHEMBL3765068)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of wild-type B-Raf (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM50146591(CHEMBL3763692)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of wild-type B-Raf (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM50146588(CHEMBL3764145)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of wild-type B-Raf (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM50146589(CHEMBL3765683)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of wild-type B-Raf (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed