Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50006468
TargetVascular endothelial growth factor receptor 2(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of VEGFR-2 (unknown origin) assessed as ATP level by luminescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of wild-type EGFR tyrosine kinase (unknown origin) assessed as ATP level by luminescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of EGFR tyrosine kinase L858R mutant (unknown origin) assessed as ATP level by luminescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50500089(CHEMBL3740910)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of wild-type EGFR tyrosine kinase (unknown origin) assessed as ATP level by luminescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50500090(CHEMBL3741473)
Affinity DataIC50: 5nMAssay Description:Inhibition of wild-type EGFR tyrosine kinase (unknown origin) assessed as ATP level by luminescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50500088(CHEMBL3740144)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of wild-type EGFR tyrosine kinase (unknown origin) assessed as ATP level by luminescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50500090(CHEMBL3741473)
Affinity DataIC50: 11nMAssay Description:Inhibition of EGFR tyrosine kinase L858R mutant (unknown origin) assessed as ATP level by luminescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50500089(CHEMBL3740910)
Affinity DataIC50: 12nMAssay Description:Inhibition of EGFR tyrosine kinase L858R mutant (unknown origin) assessed as ATP level by luminescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50500089(CHEMBL3740910)
Affinity DataIC50: 565nMAssay Description:Inhibition of VEGFR-2 (unknown origin) assessed as ATP level by luminescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50500088(CHEMBL3740144)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of VEGFR-2 (unknown origin) assessed as ATP level by luminescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed