Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50047030
TargetAminopeptidase N(Pig)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144944(CHEMBL3764919)
Affinity DataIC50: 20nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144931(CHEMBL3764432)
Affinity DataIC50: 30nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144929(CHEMBL3764200)
Affinity DataIC50: 50nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144946(CHEMBL3763918)
Affinity DataIC50: 70nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144923(CHEMBL3764156)
Affinity DataIC50: 80nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144917(CHEMBL3764826)
Affinity DataIC50: 90nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 120nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAminopeptidase N(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144944(CHEMBL3764919)
Affinity DataIC50: 120nMAssay Description:Inhibition of APN in human ES2 cells preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 1 hr by photometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144922(CHEMBL3765787)
Affinity DataIC50: 180nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144928(CHEMBL3765179)
Affinity DataIC50: 230nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144931(CHEMBL3764432)
Affinity DataIC50: 280nMAssay Description:Inhibition of APN in human ES2 cells preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 1 hr by photometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144914(CHEMBL3764417)
Affinity DataIC50: 330nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144921(CHEMBL3764011)
Affinity DataIC50: 340nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144918(CHEMBL3764391)
Affinity DataIC50: 420nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144912(CHEMBL3764097)
Affinity DataIC50: 420nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144911(CHEMBL3765592)
Affinity DataIC50: 440nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144913(CHEMBL3765067)
Affinity DataIC50: 460nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144919(CHEMBL3763451)
Affinity DataIC50: 460nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144920(CHEMBL3764325)
Affinity DataIC50: 560nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144915(CHEMBL3764075)
Affinity DataIC50: 580nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144916(CHEMBL3763665)
Affinity DataIC50: 690nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50400549(CHEMBL2205652)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Fudan University

Curated by ChEMBL
LigandPNGBDBM23971(CHEMBL29292 | (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM23971(CHEMBL29292 | (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-...)
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of APN in human ES2 cells preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 1 hr by photometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144944(CHEMBL3764919)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144929(CHEMBL3764200)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144931(CHEMBL3764432)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144919(CHEMBL3763451)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144916(CHEMBL3763665)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144915(CHEMBL3764075)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144918(CHEMBL3764391)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144917(CHEMBL3764826)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144912(CHEMBL3764097)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144911(CHEMBL3765592)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144914(CHEMBL3764417)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144913(CHEMBL3765067)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM23971(CHEMBL29292 | (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144946(CHEMBL3763918)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50400549(CHEMBL2205652)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144920(CHEMBL3764325)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144923(CHEMBL3764156)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144928(CHEMBL3765179)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144921(CHEMBL3764011)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144922(CHEMBL3765787)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed