Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50006550
TargetHistone deacetylase(Human)
Mashhad University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using BML-KI104 Fluor de Lys as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Mashhad University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataIC50: 220nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as reduction of PGE2 formation from PGH2 preincubated for 15 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Mashhad University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50500813(CHEMBL1087690)
Affinity DataIC50: 930nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as reduction of PGE2 formation from PGH2 preincubated for 15 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Mashhad University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50500810(CHEMBL3758791)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as reduction of PGE2 formation from PGH2 preincubated for 15 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Mashhad University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50500808(CHEMBL3758528)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as reduction of PGE2 formation from PGH2 preincubated for 15 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Mashhad University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50500817(CHEMBL3758432)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as reduction of PGE2 formation from PGH2 preincubated for 15 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Mashhad University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50500811(CHEMBL3759749)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as reduction of PGE2 formation from PGH2 preincubated for 15 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Mashhad University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50500816(CHEMBL3758656)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as reduction of PGE2 formation from PGH2 preincubated for 15 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Mashhad University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50500809(CHEMBL3759529)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as reduction of PGE2 formation from PGH2 preincubated for 15 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Mashhad University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50500814(CHEMBL1087807)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as reduction of PGE2 formation from PGH2 preincubated for 15 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Mashhad University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50500812(CHEMBL3758253)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as reduction of PGE2 formation from PGH2 preincubated for 15 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Mashhad University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50500815(CHEMBL3759699)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as reduction of PGE2 formation from PGH2 preincubated for 15 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Mashhad University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50500809(CHEMBL3759529)
Affinity DataIC50: 8.42E+4nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using BML-KI104 Fluor de Lys as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Mashhad University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50500811(CHEMBL3759749)
Affinity DataIC50: 1.22E+5nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using BML-KI104 Fluor de Lys as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Mashhad University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataIC50: 1.87E+5nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using BML-KI104 Fluor de Lys as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Mashhad University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50500812(CHEMBL3758253)
Affinity DataIC50: 1.88E+5nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using BML-KI104 Fluor de Lys as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Mashhad University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50500816(CHEMBL3758656)
Affinity DataIC50: 2.17E+5nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using BML-KI104 Fluor de Lys as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Mashhad University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50500814(CHEMBL1087807)
Affinity DataIC50: 3.47E+5nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using BML-KI104 Fluor de Lys as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Mashhad University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50500810(CHEMBL3758791)
Affinity DataIC50: 4.95E+5nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using BML-KI104 Fluor de Lys as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Mashhad University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50500815(CHEMBL3759699)
Affinity DataIC50: 7.86E+5nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using BML-KI104 Fluor de Lys as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Mashhad University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50500813(CHEMBL1087690)
Affinity DataIC50: 5.62E+6nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using BML-KI104 Fluor de Lys as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed