Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50006481
TargetRibonucleoside-diphosphate reductase large subunit(Human)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500165(CHEMBL3746526)
Affinity DataKd:  5.53E+4nMAssay Description:Binding affinity to human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) by tryptophan fluorescence quenching assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Human)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500168(CHEMBL3746072)
Affinity DataKd:  9.68E+3nMAssay Description:Binding affinity to human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) by tryptophan fluorescence quenching assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Human)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500171(GNF-Pf-721 | CHEMBL600902)
Affinity DataKd:  3.56E+4nMAssay Description:Binding affinity to human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) by tryptophan fluorescence quenching assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Human)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500166(CHEMBL3747319)
Affinity DataKd:  1.08E+4nMAssay Description:Binding affinity to human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) by tryptophan fluorescence quenching assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Human)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500167(CHEMBL3747291)
Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Human)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500166(CHEMBL3747319)
Affinity DataIC50: 2.36E+4nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Human)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500171(GNF-Pf-721 | CHEMBL600902)
Affinity DataIC50: 2.39E+4nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Human)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500170(CHEMBL3747217)
Affinity DataIC50: 2.72E+4nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Human)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500168(CHEMBL3746072)
Affinity DataIC50: 3.22E+4nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Human)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500174(CHEMBL3745866)
Affinity DataIC50: 3.57E+4nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Human)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500165(CHEMBL3746526)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Human)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500172(CHEMBL3746454)
Affinity DataIC50: 4.52E+4nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Human)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500173(CHEMBL3746940)
Affinity DataIC50: 4.72E+4nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Human)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500169(CHEMBL3746715)
Affinity DataIC50: 6.17E+4nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Human)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50017811(CHEMBL467 | US10155732, Compound HU | HU | hydroxy...)
Affinity DataIC50: 9.97E+5nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed