Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50047939
TargetCholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197879(CHEMBL3972214)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant BuChE expressed in HEK293 cells using S-butyrylthiocholine iodide as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] A(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] B(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM15579(US8633208, Deprenyl | CHEMBL972 | L-Deprenyl | SLG...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant MAOB using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197878(CHEMBL3961103)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant BuChE expressed in HEK293 cells using S-butyrylthiocholine iodide as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197875(CHEMBL3910142)
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197876(CHEMBL3901082)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant BuChE expressed in HEK293 cells using S-butyrylthiocholine iodide as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197875(CHEMBL3910142)
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant BuChE expressed in HEK293 cells using S-butyrylthiocholine iodide as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197880(CHEMBL3931599)
Affinity DataIC50: 64nMAssay Description:Inhibition of human recombinant BuChE expressed in HEK293 cells using S-butyrylthiocholine iodide as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197877(CHEMBL3892118)
Affinity DataIC50: 79nMAssay Description:Inhibition of human recombinant BuChE expressed in HEK293 cells using S-butyrylthiocholine iodide as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018671(CHEMBL3291019)
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197875(CHEMBL3910142)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 240 mins followed by substrate addition measured for 1 hr by hors...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197878(CHEMBL3961103)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197875(CHEMBL3910142)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 180 mins followed by substrate addition measured for 1 hr by hors...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197875(CHEMBL3910142)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 120 mins followed by substrate addition measured for 1 hr by hors...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018671(CHEMBL3291019)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human recombinant BuChE expressed in HEK293 cells using S-butyrylthiocholine iodide as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197879(CHEMBL3972214)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197875(CHEMBL3910142)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 60 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197877(CHEMBL3892118)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197875(CHEMBL3910142)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018671(CHEMBL3291019)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human recombinant BuChE expressed in HEK293 cells using S-butyrylthiocholine iodide as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197880(CHEMBL3931599)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197876(CHEMBL3901082)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018671(CHEMBL3291019)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of human recombinant MAOB using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197879(CHEMBL3972214)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of human recombinant MAOB using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197875(CHEMBL3910142)
Affinity DataIC50: 2.08E+4nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 15 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197877(CHEMBL3892118)
Affinity DataIC50: 3.56E+4nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197878(CHEMBL3961103)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197880(CHEMBL3931599)
Affinity DataIC50: 4.65E+4nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM15579(US8633208, Deprenyl | CHEMBL972 | L-Deprenyl | SLG...)
Affinity DataIC50: 5.54E+4nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197876(CHEMBL3901082)
Affinity DataIC50: 6.42E+4nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 6.55E+4nMAssay Description:Inhibition of human recombinant MAOB using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197879(CHEMBL3972214)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAOB using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197876(CHEMBL3901082)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAOB using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197880(CHEMBL3931599)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAOB using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197875(CHEMBL3910142)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAOB using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197878(CHEMBL3961103)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAOB using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197877(CHEMBL3892118)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAOB using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197875(CHEMBL3910142)
Affinity DataIC50: 1.87E+5nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate measured for 1 hr by horse-radish peroxidase/amplex red-based fluorometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM15579(US8633208, Deprenyl | CHEMBL972 | L-Deprenyl | SLG...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human recombinant BuChE expressed in HEK293 cells using S-butyrylthiocholine iodide as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM15579(US8633208, Deprenyl | CHEMBL972 | L-Deprenyl | SLG...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human recombinant BuChE expressed in HEK293 cells using S-butyrylthiocholine iodide as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197875(CHEMBL3910142)
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197875(CHEMBL3910142)
Affinity DataKi:  15nMAssay Description:Mixed-type inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 30 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197875(CHEMBL3910142)
Affinity DataKi:  52nMAssay Description:Inhibition of human recombinant BuChE expressed in HEK293 cells using S-butyrylthiocholine iodide as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
TargetCholinesterase(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50197875(CHEMBL3910142)
Affinity DataKi:  53nMAssay Description:Mixed-type inhibition of human recombinant BuChE expressed in HEK293 cells using S-butyrylthiocholine iodide as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed