Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50046777
TargetNuclear receptor subfamily 1 group I member 2(Human)
University of Ljubljana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130734BDBM50130734(CHEMBL3632931)
Affinity DataIC50: 850nMAssay Description:Antagonist activity at PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
University of Ljubljana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130717BDBM50130717(CHEMBL113650 | CHEBI:34701)
Affinity DataEC50:  1.05E+4nMAssay Description:Transactivation of full length human PXR transfected in human HepG2 cells after 18 hrs by luciferase reporter assay relative to rifaximinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
University of Ljubljana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50347620BDBM50347620(Rifacol | Rifaxidin | RIFAXIMIN)
Affinity DataEC50:  1.12E+4nMAssay Description:Transactivation of full length human PXR transfected in human HepG2 cells after 18 hrs by luciferase reporter assay relative to rifaximinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
University of Ljubljana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 20625BDBM20625(CHEMBL411 | Stilbestrol | 4-[(3E)-4-(4-hydroxyphen...)
Affinity DataIC50: 1.46E+4nMAssay Description:Antagonist activity at full length human PXR transfected in human HepG2 cells assessed as reduction in rifaximin-induced receptor transactivation aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
University of Ljubljana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130718BDBM50130718(CHEMBL3632924)
Affinity DataIC50: 2.74E+4nMAssay Description:Antagonist activity at full length human PXR transfected in human HepG2 cells assessed as reduction in rifaximin-induced receptor transactivation aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed