Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 7206
Targeto-succinylbenzoate synthase(Escherichia coli (strain K12))
Argonne National Laboratory

LigandPNGBDBM181038(OSB-AMS (1))
Affinity DataIC50: 25nMpH: 7.4Assay Description:Enzyme inhibition studies were performed in 20 mM NaHPO4 buffer (pH 7.4) containing 150 mM NaCl and 1 mM MgCl2 using a MenE-MenB coupled assay in whi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
Targeto-succinylbenzoate synthase(Escherichia coli (strain K12))
Argonne National Laboratory

LigandPNGBDBM181041(5'-O-(N-[4-(2-(2-Methoxy-3,4-dioxocyclobut-1-e...)
Affinity DataIC50: 170nMpH: 7.4Assay Description:Enzyme inhibition studies were performed in 20 mM NaHPO4 buffer (pH 7.4) containing 150 mM NaCl and 1 mM MgCl2 using a MenE-MenB coupled assay in whi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
Targeto-succinylbenzoate synthase(Escherichia coli (strain K12))
Argonne National Laboratory

LigandPNGBDBM181048(5'-O-(N-[3-(2,2-Difluoro-1-hydroxy-3-oxo-2,3-d...)
Affinity DataIC50: 1.50E+3nMpH: 7.4Assay Description:Enzyme inhibition studies were performed in 20 mM NaHPO4 buffer (pH 7.4) containing 150 mM NaCl and 1 mM MgCl2 using a MenE-MenB coupled assay in whi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
Targeto-succinylbenzoate synthase(Escherichia coli (strain K12))
Argonne National Laboratory

LigandPNGBDBM181040(5'-O-(N-[4-(2-(2H-Tetrazol-5-yl)phenyl)-4-oxob...)
Affinity DataIC50: 2.20E+3nMpH: 7.4Assay Description:Enzyme inhibition studies were performed in 20 mM NaHPO4 buffer (pH 7.4) containing 150 mM NaCl and 1 mM MgCl2 using a MenE-MenB coupled assay in whi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
Targeto-succinylbenzoate synthase(Escherichia coli (strain K12))
Argonne National Laboratory

LigandPNGBDBM181039(5'-O-(N-[4''-(3-carboxylphenyl)-4''-oxobutanoyl]su...)
Affinity DataIC50: 1.00E+5nMpH: 7.4Assay Description:Enzyme inhibition studies were performed in 20 mM NaHPO4 buffer (pH 7.4) containing 150 mM NaCl and 1 mM MgCl2 using a MenE-MenB coupled assay in whi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
Targeto-succinylbenzoate synthase(Escherichia coli (strain K12))
Argonne National Laboratory

LigandPNGBDBM181042(5'-O-(N-[4-(2-(5-Oxazolyl)phenyl)-4-oxobutanoy...)
Affinity DataIC50: 1.00E+5nMpH: 7.4Assay Description:Enzyme inhibition studies were performed in 20 mM NaHPO4 buffer (pH 7.4) containing 150 mM NaCl and 1 mM MgCl2 using a MenE-MenB coupled assay in whi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
Targeto-succinylbenzoate synthase(Escherichia coli (strain K12))
Argonne National Laboratory

LigandPNGBDBM181043(5'-O-(N-[4-(2-Nitrophenyl)-4-oxobutanoyl]sulfa...)
Affinity DataIC50: 1.00E+5nMpH: 7.4Assay Description:Enzyme inhibition studies were performed in 20 mM NaHPO4 buffer (pH 7.4) containing 150 mM NaCl and 1 mM MgCl2 using a MenE-MenB coupled assay in whi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
Targeto-succinylbenzoate synthase(Escherichia coli (strain K12))
Argonne National Laboratory

LigandPNGBDBM181044(5'-O-(N-[4-(2-Boronophenyl)-4-oxobutanoyl]sulf...)
Affinity DataIC50: 1.00E+5nMpH: 7.4Assay Description:Enzyme inhibition studies were performed in 20 mM NaHPO4 buffer (pH 7.4) containing 150 mM NaCl and 1 mM MgCl2 using a MenE-MenB coupled assay in whi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
Targeto-succinylbenzoate synthase(Escherichia coli (strain K12))
Argonne National Laboratory

LigandPNGBDBM181045(5'-O-(N-[4-Hydroxy-4-(2-(2,2,2-trifluoro-1-hyd...)
Affinity DataIC50: 1.00E+5nMpH: 7.4Assay Description:Enzyme inhibition studies were performed in 20 mM NaHPO4 buffer (pH 7.4) containing 150 mM NaCl and 1 mM MgCl2 using a MenE-MenB coupled assay in whi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
Targeto-succinylbenzoate synthase(Escherichia coli (strain K12))
Argonne National Laboratory

LigandPNGBDBM181046(5'-O-(N-[3-(3-Oxo-1,3-dihydroisobenzofuran-1-y...)
Affinity DataIC50: 1.00E+5nMpH: 7.4Assay Description:Enzyme inhibition studies were performed in 20 mM NaHPO4 buffer (pH 7.4) containing 150 mM NaCl and 1 mM MgCl2 using a MenE-MenB coupled assay in whi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
Targeto-succinylbenzoate synthase(Escherichia coli (strain K12))
Argonne National Laboratory

LigandPNGBDBM181047(5'-O-(N-[3-(1-Hydroxy-3-oxoisoindolin-1-yl)pro...)
Affinity DataIC50: 1.00E+5nMpH: 7.4Assay Description:Enzyme inhibition studies were performed in 20 mM NaHPO4 buffer (pH 7.4) containing 150 mM NaCl and 1 mM MgCl2 using a MenE-MenB coupled assay in whi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed