Compile Data Set for Download or QSAR
Report error Found 65 Enz. Inhib. hit(s) with all data for entry = 50046673
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM138204(US8871778, 161)
Affinity DataIC50: 0.700nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM138201(US8871778, 144)
Affinity DataIC50: 0.700nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM138210(US8871778, 189)
Affinity DataIC50: 1nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM138200(US8871778, 141)
Affinity DataIC50: 1nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124868(CHEMBL3622958)
Affinity DataIC50: 1.70nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124761(CHEMBL3622935)
Affinity DataIC50: 1.90nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124705(CHEMBL3622924)
Affinity DataIC50: 2.30nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124709(CHEMBL3622928)
Affinity DataIC50: 3.5nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124756(CHEMBL3622934)
Affinity DataIC50: 3.70nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124765(CHEMBL3622938)
Affinity DataIC50: 5nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124707(CHEMBL3622926)
Affinity DataIC50: 5.40nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124807(CHEMBL3622944)
Affinity DataIC50: 5.70nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124711(CHEMBL3622930)
Affinity DataIC50: 6.20nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124816(CHEMBL3622945)
Affinity DataIC50: 6.30nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124710(CHEMBL3622929)
Affinity DataIC50: 7.30nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124771(CHEMBL3622940)
Affinity DataIC50: 7.30nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124839(CHEMBL3622946)
Affinity DataIC50: 7.90nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124869(CHEMBL3622960)
Affinity DataIC50: 8nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124806(CHEMBL3622943)
Affinity DataIC50: 8.90nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124866(CHEMBL3622953)
Affinity DataIC50: 9.20nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124781(CHEMBL3622942)
Affinity DataIC50: 12nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124763(CHEMBL3622936)
Affinity DataIC50: 13nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124778(CHEMBL3622941)
Affinity DataIC50: 14nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124769(CHEMBL3622939)
Affinity DataIC50: 17nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124764(CHEMBL3622937)
Affinity DataIC50: 18nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM138203(US8871778, 160)
Affinity DataIC50: 20nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124865(CHEMBL3622951)
Affinity DataIC50: 20nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124867(CHEMBL3622954)
Affinity DataIC50: 23nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM138221(US8871778, 52)
Affinity DataIC50: 37nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124708(CHEMBL3622927)
Affinity DataIC50: 38nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM138200(US8871778, 141)
Affinity DataIC50: 38nMAssay Description:Inhibition of SYK-mediated TNFalpha production in human IgG-stimulated human THP1 cells incubated for 18 hrs by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124713(CHEMBL3622932)
Affinity DataIC50: 39nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM138210(US8871778, 189)
Affinity DataIC50: 44nMAssay Description:Inhibition of SYK-mediated TNFalpha production in human IgG-stimulated human THP1 cells incubated for 18 hrs by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124868(CHEMBL3622958)
Affinity DataIC50: 56nMAssay Description:Inhibition of SYK-mediated TNFalpha production in human IgG-stimulated human THP1 cells incubated for 18 hrs by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124841(CHEMBL3622947)
Affinity DataIC50: 61nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM138200(US8871778, 141)
Affinity DataIC50: 68nMT: 2°CAssay Description:Inhibition of human RET pre-incubated for 30 mins at room temperature before substrate addition and measured 1 hr after substrate addition by cell fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124712(CHEMBL3622931)
Affinity DataIC50: 72nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124705(CHEMBL3622924)
Affinity DataIC50: 77nMAssay Description:Inhibition of SYK-mediated TNFalpha production in human IgG-stimulated human THP1 cells incubated for 18 hrs by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM138200(US8871778, 141)
Affinity DataIC50: 78nMT: 2°CAssay Description:Inhibition of JAK3 (unknown origin) pre-incubated for 30 mins at room temperature before substrate addition and measured 1 hr after substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124847(CHEMBL3622948)
Affinity DataIC50: 101nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124856(CHEMBL3622949)
Affinity DataIC50: 145nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM138200(US8871778, 141)
Affinity DataIC50: 192nMT: 2°CAssay Description:Inhibition of KDR (unknown origin) pre-incubated for 30 mins at room temperature before substrate addition and measured 1 hr after substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124753(CHEMBL3622933)
Affinity DataIC50: 307nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124870(CHEMBL3622962)
Affinity DataIC50: 326nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124705(CHEMBL3622924)
Affinity DataIC50: 349nMT: 2°CAssay Description:Inhibition of JAK3 (unknown origin) pre-incubated for 30 mins at room temperature before substrate addition and measured 1 hr after substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124863(CHEMBL3622950)
Affinity DataIC50: 377nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124868(CHEMBL3622958)
Affinity DataIC50: 418nMT: 2°CAssay Description:Inhibition of JAK3 (unknown origin) pre-incubated for 30 mins at room temperature before substrate addition and measured 1 hr after substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM138210(US8871778, 189)
Affinity DataIC50: 478nMT: 2°CAssay Description:Inhibition of JAK3 (unknown origin) pre-incubated for 30 mins at room temperature before substrate addition and measured 1 hr after substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124868(CHEMBL3622958)
Affinity DataIC50: 653nMT: 2°CAssay Description:Inhibition of KDR (unknown origin) pre-incubated for 30 mins at room temperature before substrate addition and measured 1 hr after substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124706(CHEMBL3622925)
Affinity DataIC50: 871nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
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