Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50047580
TargetCytochrome P450 3A4(Human)
University of California Irvine

Curated by ChEMBL
LigandPNGBDBM50176903(CHEMBL3814877)
Affinity DataKd:  500nMAssay Description:Binding affinity to C-terminal four-histidine tagged human CYP3A4delta3 to 24 residues expressed in Escherichia coli assessed as spectral dissociatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 3A4(Human)
University of California Irvine

Curated by ChEMBL
LigandPNGBDBM50176904(CHEMBL3814479)
Affinity DataKd:  900nMAssay Description:Binding affinity to C-terminal four-histidine tagged human CYP3A4delta3 to 24 residues expressed in Escherichia coli assessed as spectral dissociatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 3A4(Human)
University of California Irvine

Curated by ChEMBL
LigandPNGBDBM50176905(CHEMBL3814345)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to C-terminal four-histidine tagged human CYP3A4delta3 to 24 residues expressed in Escherichia coli assessed as spectral dissociatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of California Irvine

Curated by ChEMBL
LigandPNGBDBM50176907(CHEMBL3814729)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to C-terminal four-histidine tagged human CYP3A4delta3 to 24 residues expressed in Escherichia coli assessed as spectral dissociatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of California Irvine

Curated by ChEMBL
LigandPNGBDBM50176908(CHEMBL3814075)
Affinity DataKd:  1.05E+5nMAssay Description:Binding affinity to C-terminal four-histidine tagged human CYP3A4delta3 to 24 residues expressed in Escherichia coli assessed as spectral dissociatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 3A4(Human)
University of California Irvine

Curated by ChEMBL
LigandPNGBDBM50417104(CHEMBL1256004)
Affinity DataKd:  2.50E+6nMAssay Description:Binding affinity to C-terminal four-histidine tagged human CYP3A4delta3 to 24 residues expressed in Escherichia coli assessed as spectral dissociatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of California Irvine

Curated by ChEMBL
LigandPNGBDBM50176909(CHEBI:16227 | Pyridine)
Affinity DataKd:  4.50E+6nMAssay Description:Binding affinity to C-terminal four-histidine tagged human CYP3A4delta3 to 24 residues expressed in Escherichia coli assessed as spectral dissociatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of California Irvine

Curated by ChEMBL
LigandPNGBDBM50176903(CHEMBL3814877)
Affinity DataIC50: 210nMAssay Description:Inhibition of C-terminal four-histidine tagged human CYP3A4delta3 to 24 residues expressed in Escherichia coli assessed as 7-benzyloxy-4-(trifluorome...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 3A4(Human)
University of California Irvine

Curated by ChEMBL
LigandPNGBDBM50176904(CHEMBL3814479)
Affinity DataIC50: 520nMAssay Description:Inhibition of C-terminal four-histidine tagged human CYP3A4delta3 to 24 residues expressed in Escherichia coli assessed as 7-benzyloxy-4-(trifluorome...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 3A4(Human)
University of California Irvine

Curated by ChEMBL
LigandPNGBDBM50176905(CHEMBL3814345)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of C-terminal four-histidine tagged human CYP3A4delta3 to 24 residues expressed in Escherichia coli assessed as 7-benzyloxy-4-(trifluorome...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of California Irvine

Curated by ChEMBL
LigandPNGBDBM50176908(CHEMBL3814075)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of C-terminal four-histidine tagged human CYP3A4delta3 to 24 residues expressed in Escherichia coli assessed as 7-benzyloxy-4-(trifluorome...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 3A4(Human)
University of California Irvine

Curated by ChEMBL
LigandPNGBDBM50176907(CHEMBL3814729)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of C-terminal four-histidine tagged human CYP3A4delta3 to 24 residues expressed in Escherichia coli assessed as 7-benzyloxy-4-(trifluorome...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of California Irvine

Curated by ChEMBL
LigandPNGBDBM50417104(CHEMBL1256004)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition of C-terminal four-histidine tagged human CYP3A4delta3 to 24 residues expressed in Escherichia coli assessed as 7-benzyloxy-4-(trifluorome...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of California Irvine

Curated by ChEMBL
LigandPNGBDBM50176909(CHEBI:16227 | Pyridine)
Affinity DataIC50: 4.00E+6nMAssay Description:Inhibition of C-terminal four-histidine tagged human CYP3A4delta3 to 24 residues expressed in Escherichia coli assessed as 7-benzyloxy-4-(trifluorome...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2017
Entry Details Article
PubMed