Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50046797
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Wakunaga Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50131703(CHEMBL3633520)
Affinity DataIC50: 174nMAssay Description:Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Wakunaga Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50131705(CHEMBL3633518)
Affinity DataIC50: 286nMAssay Description:Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Wakunaga Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50131702(CHEMBL3633521)
Affinity DataIC50: 411nMAssay Description:Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Wakunaga Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50131701(CHEMBL3633522)
Affinity DataIC50: 433nMAssay Description:Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Wakunaga Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366826(Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...)
Affinity DataIC50: 470nMAssay Description:Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Wakunaga Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50131704(CHEMBL3633519)
Affinity DataIC50: 553nMAssay Description:Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Wakunaga Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50131700(CHEMBL3633523)
Affinity DataIC50: 694nMAssay Description:Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details Article
PubMed