Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50046656
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123745BDBM50123745(CHEMBL3622746)
Affinity DataKi:  1nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50026174BDBM50026174(CHEMBL1271117)
Affinity DataKi:  10nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 22302BDBM22302(N-{2-[2-(1-benzofuran-2-yl)-1H-indol-3-yl]ethyl}-4...)
Affinity DataKi:  21nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123669BDBM50123669(CHEMBL3622735)
Affinity DataKi:  30nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123798BDBM50123798(CHEMBL235920)
Affinity DataKi:  73nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123672BDBM50123672(CHEMBL3622738)
Affinity DataKi:  80nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123669BDBM50123669(CHEMBL3622735)
Affinity DataIC50: 90nMAssay Description:Inhibition of human 15-LOX1 assessed as conversion of linoleic acid to 13(S)-HpODE after 10 mins by UV analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123673BDBM50123673(CHEMBL3622739)
Affinity DataKi:  100nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123670BDBM50123670(CHEMBL3622736)
Affinity DataKi:  120nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123671BDBM50123671(CHEMBL3622737)
Affinity DataKi:  170nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123672BDBM50123672(CHEMBL3622738)
Affinity DataIC50: 200nMAssay Description:Inhibition of human 15-LOX1 assessed as conversion of linoleic acid to 13(S)-HpODE after 10 mins by UV analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123674BDBM50123674(CHEMBL3622740)
Affinity DataKi:  210nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123679BDBM50123679(CHEMBL3622745)
Affinity DataKi:  220nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123675BDBM50123675(CHEMBL3622741)
Affinity DataKi:  250nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123673BDBM50123673(CHEMBL3622739)
Affinity DataIC50: 270nMAssay Description:Inhibition of human 15-LOX1 assessed as conversion of linoleic acid to 13(S)-HpODE after 10 mins by UV analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123668BDBM50123668(CHEMBL3622734)
Affinity DataKi:  290nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123670BDBM50123670(CHEMBL3622736)
Affinity DataIC50: 300nMAssay Description:Inhibition of human 15-LOX1 assessed as conversion of linoleic acid to 13(S)-HpODE after 10 mins by UV analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123678BDBM50123678(CHEMBL3622744)
Affinity DataKi:  310nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123671BDBM50123671(CHEMBL3622737)
Affinity DataIC50: 430nMAssay Description:Inhibition of human 15-LOX1 assessed as conversion of linoleic acid to 13(S)-HpODE after 10 mins by UV analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123677BDBM50123677(CHEMBL3622743)
Affinity DataKi:  480nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123674BDBM50123674(CHEMBL3622740)
Affinity DataIC50: 540nMAssay Description:Inhibition of human 15-LOX1 assessed as conversion of linoleic acid to 13(S)-HpODE after 10 mins by UV analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123679BDBM50123679(CHEMBL3622745)
Affinity DataIC50: 560nMAssay Description:Inhibition of human 15-LOX1 assessed as conversion of linoleic acid to 13(S)-HpODE after 10 mins by UV analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123675BDBM50123675(CHEMBL3622741)
Affinity DataIC50: 600nMAssay Description:Inhibition of human 15-LOX1 assessed as conversion of linoleic acid to 13(S)-HpODE after 10 mins by UV analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123667BDBM50123667(CHEMBL3622733)
Affinity DataKi:  720nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123668BDBM50123668(CHEMBL3622734)
Affinity DataIC50: 730nMAssay Description:Inhibition of human 15-LOX1 assessed as conversion of linoleic acid to 13(S)-HpODE after 10 mins by UV analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123678BDBM50123678(CHEMBL3622744)
Affinity DataIC50: 770nMAssay Description:Inhibition of human 15-LOX1 assessed as conversion of linoleic acid to 13(S)-HpODE after 10 mins by UV analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123676BDBM50123676(CHEMBL3622742)
Affinity DataKi:  830nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123666BDBM50123666(CHEMBL3622732)
Affinity DataKi:  930nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123677BDBM50123677(CHEMBL3622743)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of human 15-LOX1 assessed as conversion of linoleic acid to 13(S)-HpODE after 10 mins by UV analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123667BDBM50123667(CHEMBL3622733)
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of human 15-LOX1 assessed as conversion of linoleic acid to 13(S)-HpODE after 10 mins by UV analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123680BDBM50123680(CHEMBL3622748)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human 15-LOX1 assessed as conversion of linoleic acid to 13(S)-HpODE after 10 mins by UV analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123676BDBM50123676(CHEMBL3622742)
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of human 15-LOX1 assessed as conversion of linoleic acid to 13(S)-HpODE after 10 mins by UV analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123666BDBM50123666(CHEMBL3622732)
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of human 15-LOX1 assessed as conversion of linoleic acid to 13(S)-HpODE after 10 mins by UV analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123681BDBM50123681(CHEMBL3622749)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human 15-LOX1 assessed as conversion of linoleic acid to 13(S)-HpODE after 10 mins by UV analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208823BDBM50208823(6,11-dihydrothiochromeno[4,3-b]indole | PD-146176 ...)
Affinity DataKi:  3.81E+3nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123663BDBM50123663(CHEMBL3622747)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of 15-LOX1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123663BDBM50123663(CHEMBL3622747)
Affinity DataKi:  2.50E+4nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed