Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50046541
LigandPNGBDBM50117874(CHEMBL3612310)
Affinity DataIC50: 13nMAssay Description:Inhibition of p110alpha/p85alpha (unknown origin) incubated for 40 mins by luciferase based ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 44nMAssay Description:Inhibition of mTORC1 (unknown origin) incubated for 40 mins by luciferase based ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 49nMAssay Description:Inhibition of p110alpha/p85alpha (unknown origin) incubated for 40 mins by luciferase based ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50117874(CHEMBL3612310)
Affinity DataIC50: 78nMAssay Description:Inhibition of mTORC1 (unknown origin) incubated for 40 mins by luciferase based ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandPNGBDBM50117874(CHEMBL3612310)
Affinity DataIC50: 90nMAssay Description:Inhibition of p110beta/p85alpha (unknown origin) incubated for 40 mins by luciferase based ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 138nMAssay Description:Inhibition of p110delta/p85alpha (unknown origin) incubated for 40 mins by luciferase based ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandPNGBDBM50117874(CHEMBL3612310)
Affinity DataIC50: 148nMAssay Description:Inhibition of p110delta/p85alpha (unknown origin) incubated for 40 mins by luciferase based ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 478nMAssay Description:Inhibition of p110beta/p85alpha (unknown origin) incubated for 40 mins by luciferase based ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed