Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50046701
TargetPlatelet-derived growth factor receptor beta(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human PDGFRbeta by kinase inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human CDK1 by kinase inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of human Src kinase by kinase inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetAurora kinase A(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human AurA kinase by kinase inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human Akt1 by kinase inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human ROCK1 by kinase inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 22nMAssay Description:Inhibition of EGFR (unknown origin) using omnia tyr peptide 7 substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human MEK1 by kinase inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 55nMAssay Description:Inhibition of human FAK by kinase inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human RAF1 by kinase inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human ERK1 by kinase inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50126847(CHEMBL3628537)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50126846(CHEMBL481789)
Affinity DataIC50: 4.72E+3nMAssay Description:Inhibition of EGFR (unknown origin) using omnia tyr peptide 7 substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50126850(CHEMBL3628818)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50126851(CHEMBL3628536)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM4810(cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50126845(CHEMBL3628814)
Affinity DataIC50: 1.75E+4nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50126848(CHEMBL3628816)
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of EGFR (unknown origin) using omnia tyr peptide 7 substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50126852(CHEMBL3628817)
Affinity DataIC50: 2.16E+4nMAssay Description:Inhibition of EGFR (unknown origin) using omnia tyr peptide 7 substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50126850(CHEMBL3628818)
Affinity DataIC50: 4.57E+4nMAssay Description:Inhibition of EGFR (unknown origin) using omnia tyr peptide 7 substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50126852(CHEMBL3628817)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50126853(CHEMBL3628815)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50126849(CHEMBL3628813)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50126854(CHEMBL3628812)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50126848(CHEMBL3628816)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed